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Foxe1 Deletion in the Adult Mouse Is Associated With Increased Thyroidal Mast Cells and Hypothyroidism

CONTEXT: Foxe1 is a key thyroid developmental transcription factor. Germline deletion results in athyreosis and congenital hypothyroidism. Some data suggest an ongoing role for maintaining thyroid differentiation. OBJECTIVE: We created a mouse model to directly examine the role of Foxe1 in the adult...

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Detalles Bibliográficos
Autores principales:	Lim, Grace, Widiapradja, Alexander, Levick, Scott P, McKelvey, Kelly J, Liao, Xiao-Hui, Refetoff, Samuel, Bullock, Martyn, Clifton-Bligh, Roderick J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618408/ https://www.ncbi.nlm.nih.gov/pubmed/36156081 http://dx.doi.org/10.1210/endocr/bqac158

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