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Apixaban Use in Obese Patients: A Review of the Pharmacokinetic, Interventional, and Observational Study Data

ABSTRACT: Relatively little is known about the influence of extreme body weight on the pharmacokinetics (PK), pharmacodynamics (PD), efficacy, and safety of drugs used in many disease states. While direct oral anticoagulants (DOACs) have an advantage over warfarin in that they do not require routine...

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Detalles Bibliográficos
Autores principales: Jamieson, Michael J., Byon, Wonkyung, Dettloff, Richard W., Crawford, Matthew, Gargalovic, Peter S., Merali, Samira J., Onorato, Joelle, Quintero, Andres J., Russ, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618533/
https://www.ncbi.nlm.nih.gov/pubmed/35570249
http://dx.doi.org/10.1007/s40256-022-00524-x