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Apixaban Use in Obese Patients: A Review of the Pharmacokinetic, Interventional, and Observational Study Data
ABSTRACT: Relatively little is known about the influence of extreme body weight on the pharmacokinetics (PK), pharmacodynamics (PD), efficacy, and safety of drugs used in many disease states. While direct oral anticoagulants (DOACs) have an advantage over warfarin in that they do not require routine...
Autores principales: | Jamieson, Michael J., Byon, Wonkyung, Dettloff, Richard W., Crawford, Matthew, Gargalovic, Peter S., Merali, Samira J., Onorato, Joelle, Quintero, Andres J., Russ, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618533/ https://www.ncbi.nlm.nih.gov/pubmed/35570249 http://dx.doi.org/10.1007/s40256-022-00524-x |
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