Honing-in antigen-specific cells during antibody discovery: a user-friendly process to mine a deeper repertoire

Immunization based antibody discovery is plagued by the paucity of antigen-specific B cells. Identifying these cells is akin to finding needle in a haystack. Current and emerging technologies while effective, are limited in terms of capturing the antigen-specific repertoire. We report on the bulk pu...

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Detalles Bibliográficos
Autores principales: Mahendra, Ankit, Haque, Aftabul, Prabakaran, Ponraj, Mackness, Brian C., Fuller, Thomas P., Liu, Xiaohua, Kathuria, Sagar V., Wang, Yui-Hsi, Amatya, Nilesh, Yu, Xiaocong, Hopke, Joern, Hoffmann, Dietmar, Bric-Furlong, Eva, Zhang, Ningning, Cho, Hyun-Suk, Zhang, Ruijun, Sancho, Jose, Saleh, Jacqueline, Rao, Sambasiva P., Wendt, Maria, Chowdhury, Partha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618561/
https://www.ncbi.nlm.nih.gov/pubmed/36310321
http://dx.doi.org/10.1038/s42003-022-04129-7

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