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Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis

Autosomal dominant polycystic kidney disease (ADPKD) is the leading genetic cause of end stage renal disease characterized by progressive expansion of kidney cysts. To better understand the cell types and states driving ADPKD progression, we analyze eight ADPKD and five healthy human kidney samples,...

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Detalles Bibliográficos
Autores principales: Muto, Yoshiharu, Dixon, Eryn E., Yoshimura, Yasuhiro, Wu, Haojia, Omachi, Kohei, Ledru, Nicolas, Wilson, Parker C., King, Andrew J., Eric Olson, N., Gunawan, Marvin G., Kuo, Jay J., Cox, Jennifer H., Miner, Jeffrey H., Seliger, Stephen L., Woodward, Owen M., Welling, Paul A., Watnick, Terry J., Humphreys, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618568/
https://www.ncbi.nlm.nih.gov/pubmed/36310237
http://dx.doi.org/10.1038/s41467-022-34255-z