Cargando…
Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis
Autosomal dominant polycystic kidney disease (ADPKD) is the leading genetic cause of end stage renal disease characterized by progressive expansion of kidney cysts. To better understand the cell types and states driving ADPKD progression, we analyze eight ADPKD and five healthy human kidney samples,...
Autores principales: | Muto, Yoshiharu, Dixon, Eryn E., Yoshimura, Yasuhiro, Wu, Haojia, Omachi, Kohei, Ledru, Nicolas, Wilson, Parker C., King, Andrew J., Eric Olson, N., Gunawan, Marvin G., Kuo, Jay J., Cox, Jennifer H., Miner, Jeffrey H., Seliger, Stephen L., Woodward, Owen M., Welling, Paul A., Watnick, Terry J., Humphreys, Benjamin D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618568/ https://www.ncbi.nlm.nih.gov/pubmed/36310237 http://dx.doi.org/10.1038/s41467-022-34255-z |
Ejemplares similares
-
A single-cell multiomic analysis of kidney organoid differentiation
por: Yoshimura, Yasuhiro, et al.
Publicado: (2023) -
Left ventricular hypertrophy in a contemporary cohort of autosomal dominant polycystic kidney disease patients
por: Chen, Huanwen, et al.
Publicado: (2019) -
Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney
por: Muto, Yoshiharu, et al.
Publicado: (2021) -
The single-cell transcriptomic landscape of early human diabetic nephropathy
por: Wilson, Parker C., et al.
Publicado: (2019) -
A disease progression model estimating the benefit of tolvaptan on time to end-stage renal disease for patients with rapidly progressing autosomal dominant polycystic kidney disease
por: Mader, Gregory, et al.
Publicado: (2022)