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pH-dependent structural diversity of profilin allergens determines thermal stability

The family of profilin allergens is a common class of proteins found in plants, viruses and various eukaryotes including mammals. Profilins are characterized by an evolutionary conserved structural fold, which is responsible for their cross-reactive nature of Immunoglobulin E (IgE) antibodies. Despi...

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Detalles Bibliográficos
Autores principales: Hofer, Florian, Fischer, Anna-Lena, Kamenik, Anna S., Waibl, Franz, Fernández-Quintero, Monica L., Liedl, Klaus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618696/
https://www.ncbi.nlm.nih.gov/pubmed/36324331
http://dx.doi.org/10.3389/falgy.2022.1007000