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Models of care for improving health-related quality of life, mental health, or mortality in persons with multimorbidity: A systematic review of randomized controlled trials

OBJECTIVES: To categorize and examine the effectiveness regarding health-related quality of life (HRQoL), mental health, and mortality of care models for persons with multimorbidity in primary care, community care, and hospitals through a systematic review. METHODS: We searched PubMed, Embase, and C...

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Autores principales: Eriksen, Christian U, Kamstrup–Larsen, Nina, Birke, Hanne, Helding, Sofie A L, Ghith, Nermin, Andersen, John S, Frølich, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618762/
https://www.ncbi.nlm.nih.gov/pubmed/36325259
http://dx.doi.org/10.1177/26335565221134017
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author Eriksen, Christian U
Kamstrup–Larsen, Nina
Birke, Hanne
Helding, Sofie A L
Ghith, Nermin
Andersen, John S
Frølich, Anne
author_facet Eriksen, Christian U
Kamstrup–Larsen, Nina
Birke, Hanne
Helding, Sofie A L
Ghith, Nermin
Andersen, John S
Frølich, Anne
author_sort Eriksen, Christian U
collection PubMed
description OBJECTIVES: To categorize and examine the effectiveness regarding health-related quality of life (HRQoL), mental health, and mortality of care models for persons with multimorbidity in primary care, community care, and hospitals through a systematic review. METHODS: We searched PubMed, Embase, and Cochrane Central Register of Controlled Trials up to May 2020. One author screened titles and abstracts, and to validate, a second author screened 5% of the studies. Two authors independently extracted data and assessed risk of bias using the tool by the Cochrane Effective Practice and Organisation of Care group. Study inclusion criteria were (1) participants aged ≥ 18 years with multimorbidity; (2) referred to multimorbidity or two or more specific chronic conditions in the title or abstract; (3) randomized controlled design; and (4) HRQoL, mental health, or mortality as primary outcome measures. We used the Foundation Framework to categorize the models and the PRISMA-guideline for reporting. RESULTS: In this study, the first to report effectiveness of care models in patients with multimorbidity in hospital settings, we included 30 studies and 9,777 participants with multimorbidity. 12 studies were located in primary care, 9 in community care, and 9 in hospitals. HRQoL was reported as the primary outcome in 12 studies, mental health in 17 studies, and mortality in three studies—with significant improvements in 5, 14, and 2, respectively. The studies are presented according to settings. CONCLUSIONS: Although 20 of the care models reported positive effects, the variations in populations, settings, model elements, and outcome measures made it difficult to conclude on which models and model elements were effective.
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spelling pubmed-96187622022-11-01 Models of care for improving health-related quality of life, mental health, or mortality in persons with multimorbidity: A systematic review of randomized controlled trials Eriksen, Christian U Kamstrup–Larsen, Nina Birke, Hanne Helding, Sofie A L Ghith, Nermin Andersen, John S Frølich, Anne J Multimorb Comorb Review Article OBJECTIVES: To categorize and examine the effectiveness regarding health-related quality of life (HRQoL), mental health, and mortality of care models for persons with multimorbidity in primary care, community care, and hospitals through a systematic review. METHODS: We searched PubMed, Embase, and Cochrane Central Register of Controlled Trials up to May 2020. One author screened titles and abstracts, and to validate, a second author screened 5% of the studies. Two authors independently extracted data and assessed risk of bias using the tool by the Cochrane Effective Practice and Organisation of Care group. Study inclusion criteria were (1) participants aged ≥ 18 years with multimorbidity; (2) referred to multimorbidity or two or more specific chronic conditions in the title or abstract; (3) randomized controlled design; and (4) HRQoL, mental health, or mortality as primary outcome measures. We used the Foundation Framework to categorize the models and the PRISMA-guideline for reporting. RESULTS: In this study, the first to report effectiveness of care models in patients with multimorbidity in hospital settings, we included 30 studies and 9,777 participants with multimorbidity. 12 studies were located in primary care, 9 in community care, and 9 in hospitals. HRQoL was reported as the primary outcome in 12 studies, mental health in 17 studies, and mortality in three studies—with significant improvements in 5, 14, and 2, respectively. The studies are presented according to settings. CONCLUSIONS: Although 20 of the care models reported positive effects, the variations in populations, settings, model elements, and outcome measures made it difficult to conclude on which models and model elements were effective. SAGE Publications 2022-10-27 /pmc/articles/PMC9618762/ /pubmed/36325259 http://dx.doi.org/10.1177/26335565221134017 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review Article
Eriksen, Christian U
Kamstrup–Larsen, Nina
Birke, Hanne
Helding, Sofie A L
Ghith, Nermin
Andersen, John S
Frølich, Anne
Models of care for improving health-related quality of life, mental health, or mortality in persons with multimorbidity: A systematic review of randomized controlled trials
title Models of care for improving health-related quality of life, mental health, or mortality in persons with multimorbidity: A systematic review of randomized controlled trials
title_full Models of care for improving health-related quality of life, mental health, or mortality in persons with multimorbidity: A systematic review of randomized controlled trials
title_fullStr Models of care for improving health-related quality of life, mental health, or mortality in persons with multimorbidity: A systematic review of randomized controlled trials
title_full_unstemmed Models of care for improving health-related quality of life, mental health, or mortality in persons with multimorbidity: A systematic review of randomized controlled trials
title_short Models of care for improving health-related quality of life, mental health, or mortality in persons with multimorbidity: A systematic review of randomized controlled trials
title_sort models of care for improving health-related quality of life, mental health, or mortality in persons with multimorbidity: a systematic review of randomized controlled trials
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618762/
https://www.ncbi.nlm.nih.gov/pubmed/36325259
http://dx.doi.org/10.1177/26335565221134017
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