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Bone marrow stroma cells promote induction of a chemoresistant and prognostic unfavorable S100A8/A9(high) AML cell subset

The bone marrow (BM) stroma represents a protective niche for acute myeloid leukemia (AML) cells. However, the complex underlying mechanisms remain to be fully elucidated. We found 2 small, intracellular, calcium-sensing molecules, S100A8 and S100A9, among the top genes being upregulated in primary...

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Detalles Bibliográficos
Autores principales: Böttcher, Martin, Panagiotidis, Konstantinos, Bruns, Heiko, Stumpf, Martina, Völkl, Simon, Geyh, Stefanie, Dietel, Barbara, Schroeder, Thomas, Mackensen, Andreas, Mougiakakos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618779/
https://www.ncbi.nlm.nih.gov/pubmed/35390134
http://dx.doi.org/10.1182/bloodadvances.2021005938