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Canine induced pluripotent stem cells efficiently differentiate into definitive endoderm in 3D cell culture conditions using high-dose activin A

INTRODUCTION: Endoderm-derived organs support indispensable functions in the body. Pluripotent stem cells can generate endoderm-derived cells or tissues and have excellent therapeutic potential to replace the functions of endodermal tissues. However, there is no viable method to induce endodermal pr...

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Detalles Bibliográficos
Autores principales:	Tsukamoto, Masaya, Kimura, Kazuto, Yoshida, Takumi, Sugiura, Kikuya, Hatoya, Shingo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Society for Regenerative Medicine 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618789/ https://www.ncbi.nlm.nih.gov/pubmed/36382137 http://dx.doi.org/10.1016/j.reth.2022.10.002

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