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Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency

Lipid accumulation in nonadipose tissues can cause lipotoxicity, leading to cell death and severe organ dysfunction. Adipose triglyceride lipase (ATGL) deficiency causes human neutral lipid storage disease and leads to cardiomyopathy; ATGL deficiency has no current treatment. One possible approach t...

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Detalles Bibliográficos
Autores principales:	Oluwadare, Jide, Cabodevilla, Ainara G., Son, Ni-Huiping, Hu, Yunying, Mullick, Adam E., Verano, Michael, Alemán, Jose O., Ramasamy, Ravichandran, Goldberg, Ira J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618837/ https://www.ncbi.nlm.nih.gov/pubmed/36115595 http://dx.doi.org/10.1016/j.jlr.2022.100274

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