A 9-aminoacridine derivative induces growth inhibition of Ehrlich ascites carcinoma cells and antinociceptive effect in mice

Acridine derivatives have been found with anticancer and antinociceptive activities. Herein, we aimed to evaluate the toxicological, antitumor, and antinociceptive actions of N’-(6-chloro-2-methoxyacridin-9-yl)-2-cyanoacetohydrazide (ACS-AZ), a 9-aminoacridine derivative with antimalarial activity....

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Detalles Bibliográficos
Autores principales: Mangueira, Vivianne M., de Sousa, Tatyanna K. G., Batista, Tatianne M., de Abrantes, Renata A., Moura, Ana Paula G., Ferreira, Rafael C., de Almeida, Reinaldo N., Braga, Renan M., Leite, Fagner Carvalho, Medeiros, Karina C. de P., Cavalcanti, Misael Azevedo T., Moura, Ricardo O., Silvestre, Geovana F. G., Batista, Leônia M., Sobral, Marianna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618857/
https://www.ncbi.nlm.nih.gov/pubmed/36324671
http://dx.doi.org/10.3389/fphar.2022.963736

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