Angioimmunoblastic T-cell lymphoma with predominant CD8+ tumor-infiltrating T-cells is a distinct immune pattern with an immunosuppressive microenvironment

BACKGROUND: Angioimmunoblastic T-cell lymphoma (AITL) has a rich tumor microenvironment (TME) that typically harbors plenty of CD4+tumor infiltrating lymphocytes, (TIL)-T-cells (so called common AITL). Nonetheless, AITL with large numbers of CD8+TIL-Ts that outnumber CD4+cells have been observed (CD...

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Detalles Bibliográficos
Autores principales: Chen, Zihang, Zhu, Qiqi, Deng, Xueqin, Yao, Wenqing, Zhang, Wenyan, Liu, Weiping, Tang, Yuan, Zhao, Sha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618886/
https://www.ncbi.nlm.nih.gov/pubmed/36325319
http://dx.doi.org/10.3389/fimmu.2022.987227

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