Cargando…

Clinical, Mutational, and Transcriptomic Characteristics in Elderly Korean Individuals With Clonal Hematopoiesis Driver Mutations

BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP), which is defined as the presence of blood cells originating from somatically mutated hematopoietic stem cells, is common among the elderly and is associated with an increased risk of hematologic malignancies. We investigated the cli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moon, Inki, Kong, Min Gyu, Ji, Young Sok, Kim, Se Hyung, Park, Seong Kyu, Suh, Jon, Jang, Mi-Ae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Laboratory Medicine 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618905/ https://www.ncbi.nlm.nih.gov/pubmed/36281508 http://dx.doi.org/10.3343/alm.2023.43.2.145

Ejemplares similares

Somatic Mutations and Clonal Hematopoiesis as Drivers of Age-Related Cardiovascular Risk
por: Haring, Bernhard, et al.
Publicado: (2022)

Discovering the drivers of clonal hematopoiesis
por: Pich, Oriol, et al.
Publicado: (2022)

Clonal Hematopoiesis and Mutations of Myeloproliferative Neoplasms
por: Kjær, Lasse
Publicado: (2020)

P1337: IDENTIFICATION OF CLONAL HEMATOPOIESIS DRIVER MUTATIONS THROUGH IN SILICO SATURATION MUTAGENESIS
por: Demajo, Santiago, et al.
Publicado: (2023)

Compartment-specific mutational landscape of clonal hematopoiesis
por: Hartmann, Luise, et al.
Publicado: (2022)

Recurrent Somatic TET2 Mutations in Normal Elderly Individuals With Clonal Hematopoiesis
por: Busque, Lambert, et al.
Publicado: (2012)

Aged healthy mice acquire clonal hematopoiesis mutations
por: Chin, Desmond Wai Loon, et al.
Publicado: (2022)

Retrospective analysis of somatic mutations and clonal hematopoiesis in astronauts
por: Brojakowska, Agnieszka, et al.
Publicado: (2022)

Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis
por: Kim, Peter Geon, et al.
Publicado: (2021)

Prevalence and dynamics of clonal hematopoiesis caused by leukemia-associated mutations in elderly individuals without hematologic disorders
por: Midic, Danica, et al.
Publicado: (2020)

Chromosome Y loss and drivers of clonal hematopoiesis in myelodysplastic syndrome
por: Baliakas, Panagiotis, et al.
Publicado: (2021)

Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis
por: Inoue, Daichi, et al.
Publicado: (2016)

Mutation analysis links angioimmunoblastic T-cell lymphoma to clonal hematopoiesis and smoking
por: Cheng, Shuhua, et al.
Publicado: (2021)

Author Correction: Retrospective analysis of somatic mutations and clonal hematopoiesis in astronauts
por: Brojakowska, Agnieszka, et al.
Publicado: (2022)

Clonal Hematopoiesis Mutations Are Present in Atherosclerotic Lesions in Peripheral Artery Disease
por: Büttner, Petra, et al.
Publicado: (2023)

Clonal hematopoiesis in patients with ANKRD26 or ETV6 germline mutations
por: Drazer, Michael W., et al.
Publicado: (2022)

Clonal Hematopoiesis in Hospitalized Elderly Patients With COVID-19
por: Hameister, Erik, et al.
Publicado: (2020)

Clonal Architectures and Driver Mutations in Metastatic Melanomas
por: Ding, Li, et al.
Publicado: (2014)

Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure
por: Dorsheimer, Lena, et al.
Publicado: (2018)

PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy
por: Hsu, Joanne I., et al.
Publicado: (2018)

Chipping in on clonal hematopoiesis
por: Gillis, Nancy K., et al.
Publicado: (2017)

Evolution of clonal hematopoiesis
por: van Zeventer, Isabelle A., et al.
Publicado: (2023)

Clonal Hematopoiesis and Epigenetic Age Acceleration in Elderly Danish Twins
por: Soerensen, Mette, et al.
Publicado: (2022)

Clonal Hematopoiesis and JAK2V617F Mutations in Patients With Cardiovascular Disease
por: Yokokawa, Tetsuro, et al.
Publicado: (2021)

Clonal Hematopoiesis Mutations in Patients with Lung Cancer Are Associated with Lung Cancer Risk Factors
por: Hong, Wei, et al.
Publicado: (2022)

Troublemaking mutations: Clonal hematopoiesis for the prediction of prognosis in ST-segment elevation myocardial infarction
por: Díez-Díez, Miriam, et al.
Publicado: (2022)

Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis
por: Gao, Teng, et al.
Publicado: (2021)

Molecular Pathways in Clonal Hematopoiesis: From the Acquisition of Somatic Mutations to Transformation into Hematologic Neoplasm
por: Gaulin, Charles, et al.
Publicado: (2022)

Association of clonal hematopoiesis mutations with clinical outcomes: A systematic review and meta‐analysis
por: Nowakowska, Malgorzata K., et al.
Publicado: (2022)

Genetic Mutation Profiles in Korean Patients with Inherited Retinal Diseases
por: Kim, Min Seok, et al.
Publicado: (2019)

Clonal Hematopoiesis and Vascular Disease
por: Amancherla, Kaushik, et al.
Publicado: (2022)

Genetic Predisposition to Clonal Hematopoiesis
por: Quiros, Pedro M., et al.
Publicado: (2023)

EBV-positive DLBCL frequently harbors somatic mutations associated with clonal hematopoiesis of indeterminate potential
por: Li, Yong, et al.
Publicado: (2022)

Clonal hematopoiesis with DNMT3A mutation is associated with lower white matter hyperintensity volume
por: Lee, Woo‐Jin, et al.
Publicado: (2023)

Leukocytes carrying Clonal Hematopoiesis of Indeterminate Potential (CHIP) Mutations invade Human Atherosclerotic Plaques
por: von Scheidt, Moritz, et al.
Publicado: (2023)

Clonal hematopoiesis by DNMT3A mutations as a common finding in idiopathic splanchnic vein thrombosis
por: Carrà, Giovanna, et al.
Publicado: (2022)

Low-level somatic JAK2 V617F mutation in myelodysplastic/ myeloproliferative neoplasm with ring sideroblasts, and thrombocytosis with co-mutated SF3B1 and CALR
por: Ji, Young Sok, et al.
Publicado: (2022)

Aging of the Microenvironment Influences Clonality in Hematopoiesis
por: Vas, Virag, et al.
Publicado: (2012)

Clonal hematopoiesis in patients with rheumatoid arthritis
por: Savola, Paula, et al.
Publicado: (2018)

CLONAL HEMATOPOIESIS IN A CENTENARIAN COHORT
por: Bhutkar, Aparna, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m7esifm21oobcj0viui8od4ogv