Comorbidity between lung cancer and COVID-19 pneumonia: role of immunoregulatory gene transcripts in high ACE2-expressing normal lung

BACKGROUND: SARS-CoV-2 (COVID-19) elicits a T-cell antigen-mediated immune response of variable efficacy. To understand this variability, we explored transcriptomic expression of angiotensin-converting enzyme 2 (ACE2, the SARS-CoV-2 receptor) and of immunoregulatory genes in normal lung tissues from...

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Detalles Bibliográficos
Autores principales: Lazar, Vladimir, Raynaud, Jacques, Magidi, Shai, Bresson, Catherine, Martini, Jean-François, Galbraith, Susan, Wunder, Fanny, Onn, Amir, Batist, Gerald, Girard, Nicolas, Lassen, Ulrik, Pramesh, C. S., Al-Omari, Amal, Ikeda, Sadakatsu, Berchem, Guy, Blay, Jean-Yves, Solomon, Benjamin, Felip, Enriqueta, Tabernero, Josep, Rubin, Eitan, Philip, Thierry, Porgador, Angel, Berindan-Neagoe, Ioana, Schilsky, Richard L., Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618916/
https://www.ncbi.nlm.nih.gov/pubmed/36324736
http://dx.doi.org/10.1177/17588359221133893

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