Impact of peptide permeation enhancer on tight junctions opening cellular mechanisms

The myristoylated pentapeptide, L-R5, contains an amino acid sequence of the zeta inhibitory peptide (ZIP) portion (pseudosubstrate) of protein kinase C zeta (PKC ζ). As PKC ζ is involved in the modulation of epithelial tight junctions (TJs) through the phosphorylation of TJ proteins, L-R5 was sugge...

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Detalles Bibliográficos
Autores principales: Brunner, Joël, Schvartz, Domitille, Gouiller, Aurélie, Hainard, Alexandre, Borchard, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618981/
https://www.ncbi.nlm.nih.gov/pubmed/36324528
http://dx.doi.org/10.1016/j.bbrep.2022.101375

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