Melatonin suppresses bone marrow adiposity in ovariectomized rats by rescuing the imbalance between osteogenesis and adipogenesis through SIRT1 activation

INTRODUCTION: Accelerated imbalance between bone formation and bone resorption is associated with bone loss in postmenopausal osteoporosis. Studies have shown that this loss is accompanied by an increase in bone marrow adiposity. Melatonin was shown to improve impaired bone formation capacity of bon...

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Detalles Bibliográficos
Autores principales: Huang, Xiaoxiong, Chen, Weikai, Gu, Chao, Liu, Hao, Hou, Mingzhuang, Qin, Wanjin, Zhu, Xuesong, Chen, Xi, Liu, Tao, Yang, Huilin, He, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619141/
https://www.ncbi.nlm.nih.gov/pubmed/36381247
http://dx.doi.org/10.1016/j.jot.2022.10.002

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