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Plasticity and therapeutic potential of cAMP and cGMP-specific phosphodiesterases in Toxoplasma gondii

Toxoplasma gondii is a common zoonotic protozoan pathogen adapted to intracellular parasitism in many host cells of diverse organisms. Our previous work has identified 18 cyclic nucleotide phosphodiesterase (PDE) proteins encoded by the parasite genome, of which 11 are expressed during the lytic cyc...

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Detalles Bibliográficos
Autores principales: Vo, Kim Chi, Ruga, Liberta, Psathaki, Olympia Ekaterini, Franzkoch, Rico, Distler, Ute, Tenzer, Stefan, Hensel, Michael, Hegemann, Peter, Gupta, Nishith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619220/
https://www.ncbi.nlm.nih.gov/pubmed/36382189
http://dx.doi.org/10.1016/j.csbj.2022.09.022