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Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

Direct reprogramming of glia into neurons is a potentially promising approach for the replacement of neurons lost to injury or neurodegenerative disorders. Knockdown of the polypyrimidine tract-binding protein Ptbp1 has been recently reported to induce efficient conversion of retinal Müller glia int...

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Detalles Bibliográficos
Autores principales:	Hoang, Thanh, Won Kim, Dong, Appel, Haley, Pannullo, Nicole A., Leavey, Patrick, Ozawa, Manabu, Zheng, Sika, Yu, Minzhong, Peachey, Neal S., Blackshaw, Seth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619396/ https://www.ncbi.nlm.nih.gov/pubmed/35705053 http://dx.doi.org/10.1016/j.celrep.2022.110849

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