Development of crescentic membranoproliferative glomerulonephritis after COVID-19 vaccination

Membranoproliferative glomerulonephritis (MPGN) comprises a histologic pattern of glomerular injury with different underlying diseases. Here we report on a 47-year-old female with rapidly progressive glomerulonephritis (RPGN) on top of a previously diagnosed idiopathic MPGN after receiving the first...

Descripción completa

Detalles Bibliográficos
Autores principales: Göndör, Gabor, Ksiazek, Sara H, Regele, Heinz, Kronbichler, Andreas, Knechtelsdorfer, Maarten, Säemann, Marcus D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Exceptional Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619771/
https://www.ncbi.nlm.nih.gov/pubmed/36381369
http://dx.doi.org/10.1093/ckj/sfac222
_version_ 1784821282702884864
author Göndör, Gabor
Ksiazek, Sara H
Regele, Heinz
Kronbichler, Andreas
Knechtelsdorfer, Maarten
Säemann, Marcus D
author_facet Göndör, Gabor
Ksiazek, Sara H
Regele, Heinz
Kronbichler, Andreas
Knechtelsdorfer, Maarten
Säemann, Marcus D
author_sort Göndör, Gabor
collection PubMed
description Membranoproliferative glomerulonephritis (MPGN) comprises a histologic pattern of glomerular injury with different underlying diseases. Here we report on a 47-year-old female with rapidly progressive glomerulonephritis (RPGN) on top of a previously diagnosed idiopathic MPGN after receiving the first dose of the Pfizer-BioNTech coronavirus disease 2019 (COVID-19) mRNA vaccine. After aggressive immunosuppression her serum creatinine returned to normal values, along with reduction of proteinuria. Recently, numerous publications have reported an association of glomerular diseases with COVID-19 vaccination. Our case presents to the best of our knowledge the first occurrence of possible association of COVID-19 mRNA vaccination with a crescentic form of MPGN.
format Online
Article
Text
id pubmed-9619771
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-96197712022-11-04 Development of crescentic membranoproliferative glomerulonephritis after COVID-19 vaccination Göndör, Gabor Ksiazek, Sara H Regele, Heinz Kronbichler, Andreas Knechtelsdorfer, Maarten Säemann, Marcus D Clin Kidney J Exceptional Case Membranoproliferative glomerulonephritis (MPGN) comprises a histologic pattern of glomerular injury with different underlying diseases. Here we report on a 47-year-old female with rapidly progressive glomerulonephritis (RPGN) on top of a previously diagnosed idiopathic MPGN after receiving the first dose of the Pfizer-BioNTech coronavirus disease 2019 (COVID-19) mRNA vaccine. After aggressive immunosuppression her serum creatinine returned to normal values, along with reduction of proteinuria. Recently, numerous publications have reported an association of glomerular diseases with COVID-19 vaccination. Our case presents to the best of our knowledge the first occurrence of possible association of COVID-19 mRNA vaccination with a crescentic form of MPGN. Oxford University Press 2022-10-19 /pmc/articles/PMC9619771/ /pubmed/36381369 http://dx.doi.org/10.1093/ckj/sfac222 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the ERA. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Exceptional Case
Göndör, Gabor
Ksiazek, Sara H
Regele, Heinz
Kronbichler, Andreas
Knechtelsdorfer, Maarten
Säemann, Marcus D
Development of crescentic membranoproliferative glomerulonephritis after COVID-19 vaccination
title Development of crescentic membranoproliferative glomerulonephritis after COVID-19 vaccination
title_full Development of crescentic membranoproliferative glomerulonephritis after COVID-19 vaccination
title_fullStr Development of crescentic membranoproliferative glomerulonephritis after COVID-19 vaccination
title_full_unstemmed Development of crescentic membranoproliferative glomerulonephritis after COVID-19 vaccination
title_short Development of crescentic membranoproliferative glomerulonephritis after COVID-19 vaccination
title_sort development of crescentic membranoproliferative glomerulonephritis after covid-19 vaccination
topic Exceptional Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619771/
https://www.ncbi.nlm.nih.gov/pubmed/36381369
http://dx.doi.org/10.1093/ckj/sfac222
work_keys_str_mv AT gondorgabor developmentofcrescenticmembranoproliferativeglomerulonephritisaftercovid19vaccination
AT ksiazeksarah developmentofcrescenticmembranoproliferativeglomerulonephritisaftercovid19vaccination
AT regeleheinz developmentofcrescenticmembranoproliferativeglomerulonephritisaftercovid19vaccination
AT kronbichlerandreas developmentofcrescenticmembranoproliferativeglomerulonephritisaftercovid19vaccination
AT knechtelsdorfermaarten developmentofcrescenticmembranoproliferativeglomerulonephritisaftercovid19vaccination
AT saemannmarcusd developmentofcrescenticmembranoproliferativeglomerulonephritisaftercovid19vaccination

Ejemplares similares