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Discovery, Chemistry, and Preclinical Development of Pritelivir, a Novel Treatment Option for Acyclovir-Resistant Herpes Simplex Virus Infections

[Image: see text] When the nucleoside analogue acyclovir was introduced in the early 1980s, it presented a game-changing treatment modality for herpes simplex virus infections. Since then, work has been ongoing to improve the weaknesses that have now been identified: a narrow time window for therape...

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Detalles Bibliográficos
Autores principales:	Birkmann, Alexander, Bonsmann, Susanne, Kropeit, Dirk, Pfaff, Tamara, Rangaraju, Manickam, Sumner, Melanie, Timmler, Burkhard, Zimmermann, Holger, Buschmann, Helmut, Ruebsamen-Schaeff, Helga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620171/ https://www.ncbi.nlm.nih.gov/pubmed/36202389 http://dx.doi.org/10.1021/acs.jmedchem.2c00668

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