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Discovery of N-β-l-Fucosyl Amides as High-Affinity Ligands for the Pseudomonas aeruginosa Lectin LecB
[Image: see text] The Gram-negative pathogen Pseudomonas aeruginosa causes severe infections mainly in immunocompromised or cystic fibrosis patients and is able to resist antimicrobial treatments. The extracellular lectin LecB plays a key role in bacterial adhesion to the host and biofilm formation....
Autores principales: | Mała, Patrycja, Siebs, Eike, Meiers, Joscha, Rox, Katharina, Varrot, Annabelle, Imberty, Anne, Titz, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620277/ https://www.ncbi.nlm.nih.gov/pubmed/36256875 http://dx.doi.org/10.1021/acs.jmedchem.2c01373 |
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