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Discovery of N-β-l-Fucosyl Amides as High-Affinity Ligands for the Pseudomonas aeruginosa Lectin LecB

[Image: see text] The Gram-negative pathogen Pseudomonas aeruginosa causes severe infections mainly in immunocompromised or cystic fibrosis patients and is able to resist antimicrobial treatments. The extracellular lectin LecB plays a key role in bacterial adhesion to the host and biofilm formation....

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Detalles Bibliográficos
Autores principales: Mała, Patrycja, Siebs, Eike, Meiers, Joscha, Rox, Katharina, Varrot, Annabelle, Imberty, Anne, Titz, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620277/
https://www.ncbi.nlm.nih.gov/pubmed/36256875
http://dx.doi.org/10.1021/acs.jmedchem.2c01373

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