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Hormone replacement therapy (conjugated oestrogens plus bazedoxifene) for post-menopausal women with symptomatic hand osteoarthritis: primary report from the HOPE-e randomised, placebo-controlled, feasibility study
BACKGROUND: Symptomatic hand osteoarthritis is more common in women than in men, and its incidence increases around the age of menopause, implicating oestrogen deficiency. No randomised controlled trials of hormone replacement therapy (HRT) have been done in people with hand osteoarthritis. We aimed...
Autores principales: | Williams, Jennifer A E, Chester-Jones, Mae, Minns Lowe, Catherine, Goff, Megan V, Francis, Anne, Brewer, Gretchen, Marian, Ioana, Morris, Susan L, Warwick, Debbie, Eldridge, Lucy, Julier, Patrick, Gulati, Malvika, Barker, Karen L, Barber, Vicki S, Black, Joanna, Woollacott, Sue, Mackworth-Young, Charles, Glover, Vicki, Lamb, Sarah E, Vincent, Tonia L, Vincent, Katy, Dutton, Susan J, Watt, Fiona E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620575/ https://www.ncbi.nlm.nih.gov/pubmed/36341025 http://dx.doi.org/10.1016/S2665-9913(22)00218-1 |
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