Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies

BACKGROUND: Ganciclovir (GCV) is widely used in solid organ and haematopoietic stem cell transplant patients for prophylaxis and treatment of cytomegalovirus. It has long been considered a mutagen and carcinogen. However, the contribution of GCV to cancer incidence and other factors that influence i...

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Detalles Bibliográficos
Autores principales: Fang, Hu, Yan, Helen H. N., Bilardi, Rebecca A., Flensburg, Christoffer, Yang, Haocheng, Barbour, Jayne A., Siu, Hoi Cheong, Turski, Michelle, Chew, Edward, Xu, Zhen, Lam, Siu T., Sharma, Rakesh, Xu, Mengya, Li, Junshi, Ip, Ho W., Cheung, Carol Y. M., Huen, Michael S. Y., Sweet-Cordero, E. Alejandro, Majewski, Ian J., Leung, Suet Y., Wong, Jason W. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620652/
https://www.ncbi.nlm.nih.gov/pubmed/36316687
http://dx.doi.org/10.1186/s13073-022-01131-w

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