HMI-PRED 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry

SUMMARY: HMI-PRED 2.0 is a publicly available web service for the prediction of host–microbe protein–protein interaction by interface mimicry that is intended to be used without extensive computational experience. A microbial protein structure is screened against a database covering the entire avail...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Hansaim, Tsai, Chung-Jung, Keskin, Ozlem, Nussinov, Ruth, Gursoy, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620825/
https://www.ncbi.nlm.nih.gov/pubmed/36124958
http://dx.doi.org/10.1093/bioinformatics/btac633
Descripción
Sumario:SUMMARY: HMI-PRED 2.0 is a publicly available web service for the prediction of host–microbe protein–protein interaction by interface mimicry that is intended to be used without extensive computational experience. A microbial protein structure is screened against a database covering the entire available structural space of complexes of known human proteins. AVAILABILITY AND IMPLEMENTATION: HMI-PRED 2.0 provides user-friendly graphic interfaces for predicting, visualizing and analyzing host–microbe interactions. HMI-PRED 2.0 is available at https://hmipred.org/.

Ejemplares similares