HMI-PRED 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry

SUMMARY: HMI-PRED 2.0 is a publicly available web service for the prediction of host–microbe protein–protein interaction by interface mimicry that is intended to be used without extensive computational experience. A microbial protein structure is screened against a database covering the entire avail...

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Autores principales: Lim, Hansaim, Tsai, Chung-Jung, Keskin, Ozlem, Nussinov, Ruth, Gursoy, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620825/
https://www.ncbi.nlm.nih.gov/pubmed/36124958
http://dx.doi.org/10.1093/bioinformatics/btac633
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author Lim, Hansaim
Tsai, Chung-Jung
Keskin, Ozlem
Nussinov, Ruth
Gursoy, Attila
author_facet Lim, Hansaim
Tsai, Chung-Jung
Keskin, Ozlem
Nussinov, Ruth
Gursoy, Attila
author_sort Lim, Hansaim
collection PubMed
description SUMMARY: HMI-PRED 2.0 is a publicly available web service for the prediction of host–microbe protein–protein interaction by interface mimicry that is intended to be used without extensive computational experience. A microbial protein structure is screened against a database covering the entire available structural space of complexes of known human proteins. AVAILABILITY AND IMPLEMENTATION: HMI-PRED 2.0 provides user-friendly graphic interfaces for predicting, visualizing and analyzing host–microbe interactions. HMI-PRED 2.0 is available at https://hmipred.org/.
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spelling pubmed-96208252022-11-01 HMI-PRED 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry Lim, Hansaim Tsai, Chung-Jung Keskin, Ozlem Nussinov, Ruth Gursoy, Attila Bioinformatics Applications Notes SUMMARY: HMI-PRED 2.0 is a publicly available web service for the prediction of host–microbe protein–protein interaction by interface mimicry that is intended to be used without extensive computational experience. A microbial protein structure is screened against a database covering the entire available structural space of complexes of known human proteins. AVAILABILITY AND IMPLEMENTATION: HMI-PRED 2.0 provides user-friendly graphic interfaces for predicting, visualizing and analyzing host–microbe interactions. HMI-PRED 2.0 is available at https://hmipred.org/. Oxford University Press 2022-09-19 /pmc/articles/PMC9620825/ /pubmed/36124958 http://dx.doi.org/10.1093/bioinformatics/btac633 Text en © The Author(s) 2022. Published by Oxford University Press. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
Lim, Hansaim
Tsai, Chung-Jung
Keskin, Ozlem
Nussinov, Ruth
Gursoy, Attila
HMI-PRED 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry
title HMI-PRED 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry
title_full HMI-PRED 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry
title_fullStr HMI-PRED 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry
title_full_unstemmed HMI-PRED 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry
title_short HMI-PRED 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry
title_sort hmi-pred 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620825/
https://www.ncbi.nlm.nih.gov/pubmed/36124958
http://dx.doi.org/10.1093/bioinformatics/btac633
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