Cargando…

Identification of Drugs Associated with Lower Risk of Parkinson’s Disease Using a Systematic Screening Approach in a Nationwide Nested Case–Control Study

INTRODUCTION: Drugs for other indications may be repurposable as disease-modifying drugs for Parkinson’s disease (PD). A systematic hypothesis-free approach can enable identification of candidates for repurposing. We applied a hypothesis-free systematic approach to identify drugs associated with low...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koponen, Marjaana, Paakinaho, Anne, Lin, Julian, Hartikainen, Sirpa, Tolppanen, Anna-Maija
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620835/ https://www.ncbi.nlm.nih.gov/pubmed/36325200 http://dx.doi.org/10.2147/CLEP.S381289

Ejemplares similares

Disease-Modifying Antirheumatic Drugs and Risk of Parkinson Disease: Nested Case-Control Study of People With Rheumatoid Arthritis
por: Paakinaho, Anne, et al.
Publicado: (2022)

β2-Adrenoceptor Agonists in Asthma or Chronic Obstructive Pulmonary Disease and Risk of Parkinson’s Disease: Nested Case-Control Study
por: Paakinaho, Anne, et al.
Publicado: (2023)

Causes of death in a nationwide cohort of community-dwellers with Alzheimer’s disease
por: Tolppanen, Anna-Maija, et al.
Publicado: (2020)

Antidementia drug use among community-dwelling individuals with Alzheimer’s disease in Finland: a nationwide register-based study
por: Taipale, Heidi, et al.
Publicado: (2014)

Month and Season of Birth as a Risk Factor for Alzheimer’s Disease: A Nationwide Nested Case-control Study
por: Tolppanen, Anna-Maija, et al.
Publicado: (2016)

Association between different diabetes medication classes and risk of Parkinson's disease in people with diabetes
por: Sunnarborg, Katriina, et al.
Publicado: (2022)

Length of hospital stay after hip fracture and readmission rates of persons with and without Alzheimer’s disease: a matched cohort study
por: Rajamaki, Blair, et al.
Publicado: (2020)

Agreement between PRE2DUP register data modeling method and comprehensive drug use interview among older persons
por: Taipale, Heidi, et al.
Publicado: (2016)

From prescription drug purchases to drug use periods – a second generation method (PRE2DUP)
por: Tanskanen, Antti, et al.
Publicado: (2015)

From prescriptions to drug use periods - things to notice
por: Tanskanen, Antti, et al.
Publicado: (2014)

Drug exposure in register-based research—An expert-opinion based evaluation of methods
por: Tanskanen, Antti, et al.
Publicado: (2017)

Systemic Estrogen Use and Discontinuation After Alzheimer’s Disease Diagnosis in Finland 2005–2012: A Nationwide Exposure-Matched Cohort Study
por: Tolppanen, Anna-Maija, et al.
Publicado: (2018)

Risk of head and traumatic brain injuries associated with antidepressant use among community-dwelling persons with Alzheimer’s disease: a nationwide matched cohort study
por: Taipale, Heidi, et al.
Publicado: (2017)

Antiepileptic Drug Use Is Associated with an Increased Risk of Pneumonia Among Community-Dwelling Persons with Alzheimer’s Disease-Matched Cohort Study
por: Taipale, Heidi, et al.
Publicado: (2019)

Coronary Revascularization and Postoperative Outcomes in People With and Without Alzheimer’s Disease
por: Vu, Mai, et al.
Publicado: (2021)

Impact of High Risk Drug Use on Hospitalization and Mortality in Older People with and without Alzheimer’s Disease: A National Population Cohort Study
por: Gnjidic, Danijela, et al.
Publicado: (2014)

Use of existing data sources in clinical epidemiology: Finnish health care registers in Alzheimer’s disease research – the Medication use among persons with Alzheimer’s disease (MEDALZ-2005) study
por: Tolppanen, Anna-Maija, et al.
Publicado: (2013)

Cohort profile: the Finnish Medication and Alzheimer's disease (MEDALZ) study
por: Tolppanen, Anna-Maija, et al.
Publicado: (2016)

Length of Hospital Stay for Hip Fracture and 30-Day Mortality in People With Alzheimer’s Disease: A Cohort Study in Finland
por: Lavikainen, Piia, et al.
Publicado: (2020)

Automated multi-dose dispensing in persons with and without Alzheimer’s disease—impacts on pharmacotherapy
por: Vallius, Sanna, et al.
Publicado: (2021)

Hip Fracture Risk in Antiepileptic Drug Initiators and Non-Initiators with Alzheimer’s Disease
por: Pisa, Federica, et al.
Publicado: (2021)

Changes in the use of diabetes drugs among community-dwelling people with Alzheimer’s disease
por: López-Rubio, Carlos, et al.
Publicado: (2021)

Incidence of antidepressant use among community dwellers with and without Parkinson’s disease – a nationwide cohort study
por: Hentilä, Eerik, et al.
Publicado: (2021)

Regional changes in psychotropic use among Finnish persons with newly diagnosed Alzheimer’s disease in 2005-2011
por: Tolppanen, Anna-Maija, et al.
Publicado: (2017)

Systematic Review: Representativeness of Participants in RCTs of Acetylcholinesterase Inhibitors
por: Leinonen, Anne, et al.
Publicado: (2015)

Recent hospitalization and risk of antidepressant initiation in people with Parkinson’s disease
por: Hämäläinen, Iida, et al.
Publicado: (2022)

Psychotropic Drug-Associated Pneumonia in Older Adults
por: Rajamaki, Blair, et al.
Publicado: (2020)

Incident Hip Fractures among Community Dwelling Persons with Alzheimer’s Disease in a Finnish Nationwide Register-Based Cohort
por: Tolppanen, Anna-Maija, et al.
Publicado: (2013)

Prevalence of oral anticoagulant use among people with and without Alzheimer’s disease
por: Ali Babar, Barkat, et al.
Publicado: (2022)

The effect of comorbidities on survival in persons with Alzheimer’s disease: a matched cohort study
por: Rajamaki, Blair, et al.
Publicado: (2021)

Risk factors of pneumonia in persons with and without Alzheimer’s disease: a matched cohort study
por: Järvinen, Heli, et al.
Publicado: (2023)

History of Medically Treated Diabetes and Risk of Alzheimer Disease in a Nationwide Case-Control Study
por: Tolppanen, Anna-Maija, et al.
Publicado: (2013)

Diagnostic groups of hospital stays and outpatient visits during 10 years before Alzheimer’s disease
por: Mäklin, Kiira, et al.
Publicado: (2023)

Prevalence and characteristics of psychiatric morbidity treated in specialized health care in a nationwide cohort of people with newly diagnosed Alzheimer's disease
por: Alastalo, Aleksi, et al.
Publicado: (2022)

Antiepileptic drug use and mortality among community-dwelling persons with Alzheimer disease
por: Sarycheva, Tatyana, et al.
Publicado: (2020)

Antiepileptic Drug Use and the Risk of Stroke Among Community‐Dwelling People With Alzheimer Disease: A Matched Cohort Study
por: Sarycheva, Tatyana, et al.
Publicado: (2018)

Comparison of predictors of hip fracture and mortality after hip fracture in community-dwellers with and without Alzheimer’s disease – exposure-matched cohort study
por: Tolppanen, Anna-Maija, et al.
Publicado: (2016)

Statin discontinuation in persons with and without Alzheimer’s disease
por: Vu, Mai, et al.
Publicado: (2022)

Use of α1‐adrenoceptor antagonists tamsulosin and alfuzosin and the risk of Alzheimer's disease
por: Latvala, Laura, et al.
Publicado: (2022)

Long-term thiazide use and risk of low-energy fractures among persons with Alzheimer’s disease—nested case-control study
por: Taipale, H., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_aohggehc2hun259crns7pmi43l