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Acute encephalitis after COVID-19 vaccination: A case report and literature review
Vaccine-related immune responses are one of the causes of encephalitis. Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) have been administered worldwide due to the ongoing global pandemic; cases of SARS-CoV-2 vaccination-related encephalitis were scarcely repo...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621012/ https://www.ncbi.nlm.nih.gov/pubmed/35700455 http://dx.doi.org/10.1080/21645515.2022.2082206 |
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author | Gao, Jhih-Jian Tseng, Hung-Pin Lin, Chun-Liang Hsu, Ruei-Fong Lee, Ming-Hsun Liu, Ching-Hsiung |
author_facet | Gao, Jhih-Jian Tseng, Hung-Pin Lin, Chun-Liang Hsu, Ruei-Fong Lee, Ming-Hsun Liu, Ching-Hsiung |
author_sort | Gao, Jhih-Jian |
collection | PubMed |
description | Vaccine-related immune responses are one of the causes of encephalitis. Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) have been administered worldwide due to the ongoing global pandemic; cases of SARS-CoV-2 vaccination-related encephalitis were scarcely reported. An 82-year-old female was diagnosed with acute encephalitis following her first dose of vaccination with mRNA-1273 against SARS-CoV-2. The patient presented with fever and headache five days after vaccination, followed by behavior change 17 days after vaccination. Electroencephalographic recordings revealed focal slow waves in the right frontoparietal regions. Brain MRI revealed the signal change in the right middle and posterior temporal lobe. Cerebrospinal fluid analysis showed mildly elevated protein. She responded well to steroid pulse therapy and made a full recovery. The severity of the immune response following COVID-19 vaccination may be alleviated if adequate treatment is achieved. Physicians must be alert for encephalitis after vaccination to help ensure a favorable outcome. |
format | Online Article Text |
id | pubmed-9621012 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-96210122022-11-01 Acute encephalitis after COVID-19 vaccination: A case report and literature review Gao, Jhih-Jian Tseng, Hung-Pin Lin, Chun-Liang Hsu, Ruei-Fong Lee, Ming-Hsun Liu, Ching-Hsiung Hum Vaccin Immunother Coronavirus – Mini-Review Vaccine-related immune responses are one of the causes of encephalitis. Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) have been administered worldwide due to the ongoing global pandemic; cases of SARS-CoV-2 vaccination-related encephalitis were scarcely reported. An 82-year-old female was diagnosed with acute encephalitis following her first dose of vaccination with mRNA-1273 against SARS-CoV-2. The patient presented with fever and headache five days after vaccination, followed by behavior change 17 days after vaccination. Electroencephalographic recordings revealed focal slow waves in the right frontoparietal regions. Brain MRI revealed the signal change in the right middle and posterior temporal lobe. Cerebrospinal fluid analysis showed mildly elevated protein. She responded well to steroid pulse therapy and made a full recovery. The severity of the immune response following COVID-19 vaccination may be alleviated if adequate treatment is achieved. Physicians must be alert for encephalitis after vaccination to help ensure a favorable outcome. Taylor & Francis 2022-06-14 /pmc/articles/PMC9621012/ /pubmed/35700455 http://dx.doi.org/10.1080/21645515.2022.2082206 Text en © 2022 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. |
spellingShingle | Coronavirus – Mini-Review Gao, Jhih-Jian Tseng, Hung-Pin Lin, Chun-Liang Hsu, Ruei-Fong Lee, Ming-Hsun Liu, Ching-Hsiung Acute encephalitis after COVID-19 vaccination: A case report and literature review |
title | Acute encephalitis after COVID-19 vaccination: A case report and literature review |
title_full | Acute encephalitis after COVID-19 vaccination: A case report and literature review |
title_fullStr | Acute encephalitis after COVID-19 vaccination: A case report and literature review |
title_full_unstemmed | Acute encephalitis after COVID-19 vaccination: A case report and literature review |
title_short | Acute encephalitis after COVID-19 vaccination: A case report and literature review |
title_sort | acute encephalitis after covid-19 vaccination: a case report and literature review |
topic | Coronavirus – Mini-Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621012/ https://www.ncbi.nlm.nih.gov/pubmed/35700455 http://dx.doi.org/10.1080/21645515.2022.2082206 |
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