Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene

Genome methylation profiles define naïve-like (n-CLL), memory-like (m-CLL), and intermediate (i-CLL) subsets of chronic lymphocytic leukaemia (CLL). The profiles can be easily determined by the analysis of the five-CpG signature. m-CLL, i-CLL, and n-CLL with the good, intermediate, and poor prognose...

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Detalles Bibliográficos
Autores principales: Poppova, Lucie, Pavlova, Sarka, Gonzalez, Beatriz, Kotaskova, Jana, Plevova, Karla, Dumbovic, Gabrijela, Janovska, Pavlina, Bystry, Vojtech, Panovska, Anna, Bezdekova, Lucie, Maslejova, Stanislava, Brychtova, Yvona, Doubek, Michael, Krzyzankova, Marcela, Borsky, Marek, Mayer, Jiri, Bryja, Vitezslav, Alonso, Sergio, Pospisilova, Sarka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621079/
https://www.ncbi.nlm.nih.gov/pubmed/35333703
http://dx.doi.org/10.1080/15592294.2022.2050004

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