BAF60c prevents abdominal aortic aneurysm formation through epigenetic control of vascular smooth muscle cell homeostasis

Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease. BAF60c, a unique subunit of the SWItch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complex, is critical for cardiac and skeletal myogenesis, yet little is known about its function in the vasculature and, specifically,...

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Detalles Bibliográficos
Autores principales: Zhao, Guizhen, Zhao, Yang, Lu, Haocheng, Chang, Ziyi, Liu, Hongyu, Wang, Huilun, Liang, Wenying, Liu, Yuhao, Zhu, Tianqing, Rom, Oren, Guo, Yanhong, Chang, Lin, Yang, Bo, Garcia-Barrio, Minerva T., Lin, Jiandie D., Chen, Y. Eugene, Zhang, Jifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621131/
https://www.ncbi.nlm.nih.gov/pubmed/36066968
http://dx.doi.org/10.1172/JCI158309

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