GPR92 activation in islet macrophages controls β cell function in a diet-induced obesity model

The molecular mechanisms underlying obesity-induced increases in β cell mass and the resulting β cell dysfunction need to be elucidated further. Our study revealed that GPR92, expressed in islet macrophages, is modulated by dietary interventions in metabolic tissues. Therefore, we aimed to define th...

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Detalles Bibliográficos
Autores principales: de Souza, Camila O., Paschoal, Vivian A., Sun, Xuenan, Vishvanath, Lavanya, Zhang, Qianbin, Shao, Mengle, Onodera, Toshiharu, Chen, Shiuhwei, Joffin, Nolwenn, Bueno, Lorena M.A., Gupta, Rana K., Oh, Da Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621135/
https://www.ncbi.nlm.nih.gov/pubmed/36066975
http://dx.doi.org/10.1172/JCI160097

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