The druggable transcription factor Fli-1 regulates T cell immunity and tolerance in graft-versus-host disease

Graft-versus-host disease (GVHD), manifesting as either acute (aGVHD) or chronic (cGVHD), presents significant life-threatening complications following allogeneic hematopoietic cell transplantation. Here, we investigated Friend virus leukemia integration 1 (Fli-1) in GVHD pathogenesis and validated...

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Detalles Bibliográficos
Autores principales: Schutt, Steven D., Wu, Yongxia, Kharel, Arjun, Bastian, David, Choi, Hee-Jin, Hanief Sofi, Mohammed, Mealer, Corey, McDaniel Mims, Brianyell, Nguyen, Hung, Liu, Chen, Helke, Kris, Cui, Weiguo, Zhang, Xian, Ben-David, Yaacov, Yu, Xue-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621143/
https://www.ncbi.nlm.nih.gov/pubmed/36074578
http://dx.doi.org/10.1172/JCI143950

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