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MRI-negative myelitis associated with cerebral venous thrombosis after COVID-19 infection

Transverse myelitis and cerebral venous thrombosis represent some of the described neurological complications of coronavirus disease. A woman in her early 30s presented with headache, left-sided sensory symptoms and voiding difficulty. The patient also reported dry cough, fever, nasal congestion, an...

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Autores principales: Masaad, Dea, Youssef, Shaza, Safadi, Mhd Firas, Shehadeh Agha, Mohamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621158/
https://www.ncbi.nlm.nih.gov/pubmed/36307141
http://dx.doi.org/10.1136/bcr-2022-250535
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author Masaad, Dea
Youssef, Shaza
Safadi, Mhd Firas
Shehadeh Agha, Mohamad
author_facet Masaad, Dea
Youssef, Shaza
Safadi, Mhd Firas
Shehadeh Agha, Mohamad
author_sort Masaad, Dea
collection PubMed
description Transverse myelitis and cerebral venous thrombosis represent some of the described neurological complications of coronavirus disease. A woman in her early 30s presented with headache, left-sided sensory symptoms and voiding difficulty. The patient also reported dry cough, fever, nasal congestion, anosmia and ageusia 2 weeks before presentation. The clinical examination showed sensory disturbances on the left side of the body, starting from the lower abdomen and extending to the left leg, which was consistent with transverse myelitis. The laboratory assessment confirmed a previous infection with coronavirus disease and excluded autoimmune entities. Radiological investigations revealed left transverse sinus thrombosis with no spinal cord abnormalities. The treatment was started with therapeutic anticoagulation and intravenous high-dose steroids. The patient showed significant improvement, and the neurological deficits resolved after 3 months. This is the first documented case of imaging-negative myelitis associated with cerebral venous thrombosis after coronavirus disease.
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spelling pubmed-96211582022-11-01 MRI-negative myelitis associated with cerebral venous thrombosis after COVID-19 infection Masaad, Dea Youssef, Shaza Safadi, Mhd Firas Shehadeh Agha, Mohamad BMJ Case Rep Case Reports: Unusual presentation of more common disease/injury Transverse myelitis and cerebral venous thrombosis represent some of the described neurological complications of coronavirus disease. A woman in her early 30s presented with headache, left-sided sensory symptoms and voiding difficulty. The patient also reported dry cough, fever, nasal congestion, anosmia and ageusia 2 weeks before presentation. The clinical examination showed sensory disturbances on the left side of the body, starting from the lower abdomen and extending to the left leg, which was consistent with transverse myelitis. The laboratory assessment confirmed a previous infection with coronavirus disease and excluded autoimmune entities. Radiological investigations revealed left transverse sinus thrombosis with no spinal cord abnormalities. The treatment was started with therapeutic anticoagulation and intravenous high-dose steroids. The patient showed significant improvement, and the neurological deficits resolved after 3 months. This is the first documented case of imaging-negative myelitis associated with cerebral venous thrombosis after coronavirus disease. BMJ Publishing Group 2022-10-28 /pmc/articles/PMC9621158/ /pubmed/36307141 http://dx.doi.org/10.1136/bcr-2022-250535 Text en © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ.
spellingShingle Case Reports: Unusual presentation of more common disease/injury
Masaad, Dea
Youssef, Shaza
Safadi, Mhd Firas
Shehadeh Agha, Mohamad
MRI-negative myelitis associated with cerebral venous thrombosis after COVID-19 infection
title MRI-negative myelitis associated with cerebral venous thrombosis after COVID-19 infection
title_full MRI-negative myelitis associated with cerebral venous thrombosis after COVID-19 infection
title_fullStr MRI-negative myelitis associated with cerebral venous thrombosis after COVID-19 infection
title_full_unstemmed MRI-negative myelitis associated with cerebral venous thrombosis after COVID-19 infection
title_short MRI-negative myelitis associated with cerebral venous thrombosis after COVID-19 infection
title_sort mri-negative myelitis associated with cerebral venous thrombosis after covid-19 infection
topic Case Reports: Unusual presentation of more common disease/injury
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621158/
https://www.ncbi.nlm.nih.gov/pubmed/36307141
http://dx.doi.org/10.1136/bcr-2022-250535
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