Cargando…

Design and synthesis of some new benzoylthioureido benzenesulfonamide derivatives and their analogues as carbonic anhydrase inhibitors

The present investigation reports the design and synthesis of three series of benzoylthioureido derivatives bearing either benzenesulfonamide 7a–f, benzoic acid 8a–f or ethylbenzoate 9a–f moieties. The synthesised compounds were screened for their carbonic anhydrase inhibitory activity (CAI) against...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oudah, Khulood H., Mahmoud, Walaa R., Awadallah, Fadi M., Taher, Azza T., Abbas, Safinaz E.-S, Allam, Heba Abdelrasheed, Vullo, Daniela, Supuran, Claudiu T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621292/ https://www.ncbi.nlm.nih.gov/pubmed/36305274 http://dx.doi.org/10.1080/14756366.2022.2132485

Ejemplares similares

Design and synthesis of some new benzoylthioureido phenyl derivatives targeting carbonic anhydrase enzymes
por: Najm, Mazin A. A., et al.
Publicado: (2022)

Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors
por: Peerzada, Mudasir Nabi, et al.
Publicado: (2023)

4-(3-Alkyl/benzyl-guanidino)benzenesulfonamides as selective carbonic anhydrase VII inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2022)

Benzenesulfonamides Incorporating Hydantoin Moieties Effectively Inhibit Eukaryoticand Human Carbonic Anhydrases
por: Abdoli, Morteza, et al.
Publicado: (2022)

Effect of hydrophobic extension of aryl enaminones and pyrazole-linked compounds combined with sulphonamide, sulfaguanidine, or carboxylic acid functionalities on carbonic anhydrase inhibitory potency and selectivity
por: Allam, Heba Abdelrasheed, et al.
Publicado: (2023)

Carbonic anhydrase inhibition with a series of novel benzenesulfonamide-triazole conjugates
por: El-Gazzar, Marwa G., et al.
Publicado: (2018)

Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives
por: Gitto, Rosaria, et al.
Publicado: (2019)

Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails
por: Awadallah, Fadi M., et al.
Publicado: (2018)

Diversely N-substituted benzenesulfonamides dissimilarly bind to human carbonic anhydrases: crystallographic investigations of N-nitrosulfonamides
por: Angeli, Andrea, et al.
Publicado: (2023)

Screening of benzenesulfonamide in combination with chemically diverse fragments against carbonic anhydrase by differential scanning fluorimetry
por: Krasavin, Mikhail, et al.
Publicado: (2019)

Inhibition of bacterial α-, β- and γ-class carbonic anhydrases with selenazoles incorporating benzenesulfonamide moieties
por: Angeli, Andrea, et al.
Publicado: (2018)

Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases
por: Ali, Majid, et al.
Publicado: (2020)

Carbonic Anhydrase Inhibition Activities of Schiff’s Bases Based on Quinazoline-Linked Benzenesulfonamide
por: El-Azab, Adel S., et al.
Publicado: (2022)

Evaluation of Thio- and Seleno-Acetamides Bearing Benzenesulfonamide as Inhibitor of Carbonic Anhydrases from Different Pathogenic Bacteria
por: Angeli, Andrea, et al.
Publicado: (2020)

Hypoxia-Activated Prodrug Derivatives of Carbonic Anhydrase Inhibitors in Benzenesulfonamide Series: Synthesis and Biological Evaluation
por: Anduran, Emilie, et al.
Publicado: (2020)

Potent carbonic anhydrase I, II, IX and XII inhibition activity of novel primary benzenesulfonamides incorporating bis-ureido moieties
por: Tekeli, Tuba, et al.
Publicado: (2023)

Natural Product Polyamines That Inhibit Human Carbonic Anhydrases
por: Davis, Rohan A., et al.
Publicado: (2014)

Synthetic Strategies and Computational Inhibition Activity Study for Triazinyl-Substituted Benzenesulfonamide Conjugates with Polar and Hydrophobic Amino Acids as Inhibitors of Carbonic Anhydrases
por: Mikulová, Mária Bodnár, et al.
Publicado: (2020)

Carbonic anhydrase inhibitory properties of some uracil derivatives
por: Alper Türkoğlu, Emir, et al.
Publicado: (2017)

Design, Synthesis and Biological Assessment of Rhodanine-Linked Benzenesulfonamide Derivatives as Selective and Potent Human Carbonic Anhydrase Inhibitors
por: Swain, Baijayantimala, et al.
Publicado: (2022)

Benzenesulfonamides with different rigidity-conferring linkers as carbonic anhydrase inhibitors: an insight into the antiproliferative effect on glioblastoma, pancreatic, and breast cancer cells
por: Liguori, Francesco, et al.
Publicado: (2022)

Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani
por: Nocentini, Alessio, et al.
Publicado: (2019)

Design, synthesis, and carbonic anhydrase inhibition activities of Schiff bases incorporating benzenesulfonamide scaffold: Molecular docking application
por: El-Azab, Adel S., et al.
Publicado: (2023)

Identification of Novel and Potent Indole-Based Benzenesulfonamides as Selective Human Carbonic Anhydrase II Inhibitors: Design, Synthesis, In Vitro, and In Silico Studies
por: Elkamhawy, Ahmed, et al.
Publicado: (2022)

An anion and small molecule inhibition study of the β-carbonic anhydrase from Staphylococcus aureus
por: Urbanski, Linda J., et al.
Publicado: (2021)

Carbonic Anhydrases and Metabolism
por: Supuran, Claudiu T.
Publicado: (2018)

Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors
por: Al-Sanea, Mohammad M., et al.
Publicado: (2019)

Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships
por: Fantacuzzi, Marialuigia, et al.
Publicado: (2023)

Anion inhibition studies of a beta carbonic anhydrase from the malaria mosquito Anopheles gambiae
por: Vullo, Daniela, et al.
Publicado: (2018)

Sulfonamide inhibition studies of two β-carbonic anhydrases from the ascomycete fungus Sordaria macrospora, CAS1 and CAS2
por: Vullo, Daniela, et al.
Publicado: (2018)

4-Anilinoquinazoline-based benzenesulfonamides as nanomolar inhibitors of carbonic anhydrase isoforms I, II, IX, and XII: design, synthesis, in-vitro, and in-silico biological studies
por: Nada, Hossam, et al.
Publicado: (2022)

Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII
por: Cau, Ylenia, et al.
Publicado: (2017)

Synthesis and biological evaluation of histamine Schiff bases as carbonic anhydrase I, II, IV, VII, and IX activators
por: Akocak, Suleyman, et al.
Publicado: (2017)

An Overview of the Bacterial Carbonic Anhydrases
por: Supuran, Claudiu T., et al.
Publicado: (2017)

Sulphonamide inhibition studies of the β-carbonic anhydrase from the bacterial pathogen Clostridium perfringens
por: Vullo, Daniela, et al.
Publicado: (2017)

Sulfonamide Inhibition Studies of the β-Class Carbonic Anhydrase CAS3 from the Filamentous Ascomycete Sordaria macrospora
por: Vullo, Daniela, et al.
Publicado: (2020)

Anion Inhibition Studies of the β-Class Carbonic Anhydrase CAS3 from the Filamentous Ascomycete Sordaria macrospora
por: Vullo, Daniela, et al.
Publicado: (2020)

Carbonic Anhydrase Inhibition and the Management of Hypoxic Tumors
por: Supuran, Claudiu T.
Publicado: (2017)

Ascaris lumbricoides β carbonic anhydrase: a potential target enzyme for treatment of ascariasis
por: Zolfaghari Emameh, Reza, et al.
Publicado: (2015)

Membrane Permeability Is Required for the Vasodilatory Effect of Carbonic Anhydrase Inhibitors in Porcine Retinal Arteries
por: Eysteinsson, Thor, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v19aeqs5rlb8s4bivnvshtmee2