Cargando…

Implantable cardioverter-defibrillator therapy after resuscitation from cardiac arrest in vasospastic angina: A retrospective study

Patients with vasospastic angina (VSA) who are resuscitated from sudden cardiac arrest (SCA) are at a high risk of recurrent lethal arrhythmia and cardiovascular events. However, the benefit of the implantable cardioverter-defibrillator (ICD) therapy in this population has not been fully elucidated....

Descripción completa

Detalles Bibliográficos
Autores principales: Tateishi, Kazuya, Kondo, Yusuke, Saito, Yuichi, Kitahara, Hideki, Fukushima, Kenichi, Takahashi, Hidehisa, Yamashita, Daichi, Ohashi, Koichi, Suzuki, Ko, Hashimoto, Osamu, Sakai, Yoshiaki, Kobayashi, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621437/
https://www.ncbi.nlm.nih.gov/pubmed/36315563
http://dx.doi.org/10.1371/journal.pone.0277034
_version_ 1784821554138316800
author Tateishi, Kazuya
Kondo, Yusuke
Saito, Yuichi
Kitahara, Hideki
Fukushima, Kenichi
Takahashi, Hidehisa
Yamashita, Daichi
Ohashi, Koichi
Suzuki, Ko
Hashimoto, Osamu
Sakai, Yoshiaki
Kobayashi, Yoshio
author_facet Tateishi, Kazuya
Kondo, Yusuke
Saito, Yuichi
Kitahara, Hideki
Fukushima, Kenichi
Takahashi, Hidehisa
Yamashita, Daichi
Ohashi, Koichi
Suzuki, Ko
Hashimoto, Osamu
Sakai, Yoshiaki
Kobayashi, Yoshio
author_sort Tateishi, Kazuya
collection PubMed
description Patients with vasospastic angina (VSA) who are resuscitated from sudden cardiac arrest (SCA) are at a high risk of recurrent lethal arrhythmia and cardiovascular events. However, the benefit of the implantable cardioverter-defibrillator (ICD) therapy in this population has not been fully elucidated. The present study aimed to analyze the prognostic impact of ICD therapy on patients with VSA and SCA. A total of 280 patients who were resuscitated from SCA and received an ICD for secondary prophylaxis were included in the present multicenter registry. The patients were divided into two groups on the basis of the presence of VSA. The primary endpoint was a composite of all-cause death and appropriate ICD therapy (appropriate anti-tachycardia pacing and shock) for recurrent ventricular arrhythmias. Of 280 patients, 51 (18%) had VSA. Among those without VSA, ischemic cardiomyopathy was the main cause of SCA (38%), followed by non-ischemic cardiomyopathies (18%) and Brugada syndrome (7%). Twenty-three (8%) patients were dead and 72 (26%) received appropriate ICD therapy during a median follow-up period of 3.8 years. There was no significant difference in the incidence of the primary endpoint between patients with and without VSA (24% vs. 33%, p = 0.19). In a cohort of patients who received an ICD for secondary prophylaxis, long-term clinical outcomes were not different between those with VSA and those with other cardiac diseases after SCA, suggesting ICD therapy may be considered in patients with VSA and those with other etiologies who were resuscitated from SCA.
format Online
Article
Text
id pubmed-9621437
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-96214372022-11-01 Implantable cardioverter-defibrillator therapy after resuscitation from cardiac arrest in vasospastic angina: A retrospective study Tateishi, Kazuya Kondo, Yusuke Saito, Yuichi Kitahara, Hideki Fukushima, Kenichi Takahashi, Hidehisa Yamashita, Daichi Ohashi, Koichi Suzuki, Ko Hashimoto, Osamu Sakai, Yoshiaki Kobayashi, Yoshio PLoS One Research Article Patients with vasospastic angina (VSA) who are resuscitated from sudden cardiac arrest (SCA) are at a high risk of recurrent lethal arrhythmia and cardiovascular events. However, the benefit of the implantable cardioverter-defibrillator (ICD) therapy in this population has not been fully elucidated. The present study aimed to analyze the prognostic impact of ICD therapy on patients with VSA and SCA. A total of 280 patients who were resuscitated from SCA and received an ICD for secondary prophylaxis were included in the present multicenter registry. The patients were divided into two groups on the basis of the presence of VSA. The primary endpoint was a composite of all-cause death and appropriate ICD therapy (appropriate anti-tachycardia pacing and shock) for recurrent ventricular arrhythmias. Of 280 patients, 51 (18%) had VSA. Among those without VSA, ischemic cardiomyopathy was the main cause of SCA (38%), followed by non-ischemic cardiomyopathies (18%) and Brugada syndrome (7%). Twenty-three (8%) patients were dead and 72 (26%) received appropriate ICD therapy during a median follow-up period of 3.8 years. There was no significant difference in the incidence of the primary endpoint between patients with and without VSA (24% vs. 33%, p = 0.19). In a cohort of patients who received an ICD for secondary prophylaxis, long-term clinical outcomes were not different between those with VSA and those with other cardiac diseases after SCA, suggesting ICD therapy may be considered in patients with VSA and those with other etiologies who were resuscitated from SCA. Public Library of Science 2022-10-31 /pmc/articles/PMC9621437/ /pubmed/36315563 http://dx.doi.org/10.1371/journal.pone.0277034 Text en © 2022 Tateishi et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Tateishi, Kazuya
Kondo, Yusuke
Saito, Yuichi
Kitahara, Hideki
Fukushima, Kenichi
Takahashi, Hidehisa
Yamashita, Daichi
Ohashi, Koichi
Suzuki, Ko
Hashimoto, Osamu
Sakai, Yoshiaki
Kobayashi, Yoshio
Implantable cardioverter-defibrillator therapy after resuscitation from cardiac arrest in vasospastic angina: A retrospective study
title Implantable cardioverter-defibrillator therapy after resuscitation from cardiac arrest in vasospastic angina: A retrospective study
title_full Implantable cardioverter-defibrillator therapy after resuscitation from cardiac arrest in vasospastic angina: A retrospective study
title_fullStr Implantable cardioverter-defibrillator therapy after resuscitation from cardiac arrest in vasospastic angina: A retrospective study
title_full_unstemmed Implantable cardioverter-defibrillator therapy after resuscitation from cardiac arrest in vasospastic angina: A retrospective study
title_short Implantable cardioverter-defibrillator therapy after resuscitation from cardiac arrest in vasospastic angina: A retrospective study
title_sort implantable cardioverter-defibrillator therapy after resuscitation from cardiac arrest in vasospastic angina: a retrospective study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621437/
https://www.ncbi.nlm.nih.gov/pubmed/36315563
http://dx.doi.org/10.1371/journal.pone.0277034
work_keys_str_mv AT tateishikazuya implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy
AT kondoyusuke implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy
AT saitoyuichi implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy
AT kitaharahideki implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy
AT fukushimakenichi implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy
AT takahashihidehisa implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy
AT yamashitadaichi implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy
AT ohashikoichi implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy
AT suzukiko implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy
AT hashimotoosamu implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy
AT sakaiyoshiaki implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy
AT kobayashiyoshio implantablecardioverterdefibrillatortherapyafterresuscitationfromcardiacarrestinvasospasticanginaaretrospectivestudy