Aberrant activation of TGF-β1 induces high bone turnover via Rho GTPases-mediated cytoskeletal remodeling in Camurati-Engelmann disease

In the adult skeleton, the bone remodeling process involves a dynamic coordination between osteoblasts and osteoclasts, which is disrupted in diseases with high bone turnover rates and dysregulated transforming growth factor beta 1 (TGF-β1). However, little is known about how TGF-β1 signaling mediat...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Yao, Yan, Chen, Kun, Chen, Xihui, Li, Bowen, Li, Rui, Mo, Lidangzhi, Hu, Weihong, Zhang, Mengjie, Wang, Zhen, Wu, Yaoping, Wu, Yuanming, Liu, Fangfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621586/
https://www.ncbi.nlm.nih.gov/pubmed/36325441
http://dx.doi.org/10.3389/fendo.2022.913979

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