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Patients With Severe Multiple Sclerosis Exhibit Functionally Altered CD8(+) Regulatory T Cells

BACKGROUND AND OBJECTIVES: Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the CNS. Studies of immune dysfunction in MS have mostly focused on CD4(+) Tregs, but the role of CD8(+) Tregs remains largely unexplored. We previously evidenced the suppressive properties of r...

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Detalles Bibliográficos
Autores principales:	Benallegue, Nail, Nicol, Bryan, Lasselin, Juliette, Bézie, Severine, Flippe, Lea, Regue, Hadrien, Vimond, Nadege, Remy, Severine, Garcia, Alexandra, Le Frère, Fabienne, Anegon, Ignacio, Laplaud, David, Guillonneau, Carole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621606/ https://www.ncbi.nlm.nih.gov/pubmed/36266052 http://dx.doi.org/10.1212/NXI.0000000000200016

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