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Preparation of aripiprazole-poly(methyl vinyl ether-co-maleic anhydride) nanocomposites via supercritical antisolvent process for improved antidepression therapy

Aripiprazole (ARI), a second-generation atypical antipsychotic drug approved for schizophrenia treatment, shows good efficacy against depression. However, the poorly aqueous solubility of ARI leads to low bioavailability and increased dose-related side effects, seriously limiting its application in...

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Detalles Bibliográficos
Autores principales:	Chen, Lin-Fei, Chen, Ying, Duan, You-Yu, Zhang, Man-Man, Xu, Pei-Yao, Kankala, Ranjith Kumar, Wang, Shi-Bin, Chen, Ai-Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621701/ https://www.ncbi.nlm.nih.gov/pubmed/36330352 http://dx.doi.org/10.1093/rb/rbac080

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