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Patients With Previous COVID-19 Infection Can Safely Undergo Primary Total Joint Arthroplasty

BACKGROUND: The COVID-19 virus is believed to increase the risk of diffusing intravascular coagulation. Total joint arthroplasty (TJA) is one of the most common elective surgeries and is also associated with a temporarily increased risk of venous thromboembolism (VTE). However, the influence of a hi...

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Autores principales: Rosas, Samuel, Pollock, David C., Roche, Martin W., Najafi, Farideh, Hollingsworth, Neusha, Buller, Leonard T., Krueger, Chad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622022/
https://www.ncbi.nlm.nih.gov/pubmed/36328105
http://dx.doi.org/10.1016/j.arth.2022.10.041
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author Rosas, Samuel
Pollock, David C.
Roche, Martin W.
Najafi, Farideh
Hollingsworth, Neusha
Buller, Leonard T.
Krueger, Chad A.
author_facet Rosas, Samuel
Pollock, David C.
Roche, Martin W.
Najafi, Farideh
Hollingsworth, Neusha
Buller, Leonard T.
Krueger, Chad A.
author_sort Rosas, Samuel
collection PubMed
description BACKGROUND: The COVID-19 virus is believed to increase the risk of diffusing intravascular coagulation. Total joint arthroplasty (TJA) is one of the most common elective surgeries and is also associated with a temporarily increased risk of venous thromboembolism (VTE). However, the influence of a history of COVID-19 infection on perioperative outcomes following TJA remains unknown. Therefore, this study sought to determine what effect a history of COVID-19 infection had on outcomes following primary TJA. METHODS: A retrospective case-control study using the national database was performed to identify all patients who had a history of COVID-19 and had undergone TJA, between 2019 and 2020. Patients who had a history of both were 1:1 matched to those who did not have a history of COVID-19, and 90-day outcomes were compared. A total of 661 TKA and 635 THA patients who had a history of COVID-19 were 1:1 matched to controls. There were no differences in demographics and comorbidities between the propensity-matched pairs in both TKAs and THAs studied. Previous COVID-19 diagnosis was noted in 28.3% of patients 5 days within TJA and in 78.6%, 90 days before TJA. RESULTS: Patients who had a previous diagnosis of COVID-19 had a higher risk of pneumonia during the postoperative period for both THA and TKA (6.9% versus 3.5%, P < .001 and 2.27% versus 1.21%, P = .04, respectively). Mean lengths of stay were also greater for those with a previous COVID-19 infection in both cohorts (TKA: 3.12 versus 2.57, P = .027, THA: 4.52 versus 3.62, P < .001). Other postoperative outcomes were similar between the 2 groups. CONCLUSION: COVID-19 infection history does not appear to increase the risk of VTE following primary TJA, but appears to increase the risk of pneumonia in addition to lengths of stay postoperatively. Individual risk factors should be discussed with patients, to set reasonable expectations regarding perioperative outcomes.
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spelling pubmed-96220222022-11-01 Patients With Previous COVID-19 Infection Can Safely Undergo Primary Total Joint Arthroplasty Rosas, Samuel Pollock, David C. Roche, Martin W. Najafi, Farideh Hollingsworth, Neusha Buller, Leonard T. Krueger, Chad A. J Arthroplasty Primary Hip and Knee Arthroplasty BACKGROUND: The COVID-19 virus is believed to increase the risk of diffusing intravascular coagulation. Total joint arthroplasty (TJA) is one of the most common elective surgeries and is also associated with a temporarily increased risk of venous thromboembolism (VTE). However, the influence of a history of COVID-19 infection on perioperative outcomes following TJA remains unknown. Therefore, this study sought to determine what effect a history of COVID-19 infection had on outcomes following primary TJA. METHODS: A retrospective case-control study using the national database was performed to identify all patients who had a history of COVID-19 and had undergone TJA, between 2019 and 2020. Patients who had a history of both were 1:1 matched to those who did not have a history of COVID-19, and 90-day outcomes were compared. A total of 661 TKA and 635 THA patients who had a history of COVID-19 were 1:1 matched to controls. There were no differences in demographics and comorbidities between the propensity-matched pairs in both TKAs and THAs studied. Previous COVID-19 diagnosis was noted in 28.3% of patients 5 days within TJA and in 78.6%, 90 days before TJA. RESULTS: Patients who had a previous diagnosis of COVID-19 had a higher risk of pneumonia during the postoperative period for both THA and TKA (6.9% versus 3.5%, P < .001 and 2.27% versus 1.21%, P = .04, respectively). Mean lengths of stay were also greater for those with a previous COVID-19 infection in both cohorts (TKA: 3.12 versus 2.57, P = .027, THA: 4.52 versus 3.62, P < .001). Other postoperative outcomes were similar between the 2 groups. CONCLUSION: COVID-19 infection history does not appear to increase the risk of VTE following primary TJA, but appears to increase the risk of pneumonia in addition to lengths of stay postoperatively. Individual risk factors should be discussed with patients, to set reasonable expectations regarding perioperative outcomes. Elsevier Inc. 2023-04 2022-11-01 /pmc/articles/PMC9622022/ /pubmed/36328105 http://dx.doi.org/10.1016/j.arth.2022.10.041 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Primary Hip and Knee Arthroplasty
Rosas, Samuel
Pollock, David C.
Roche, Martin W.
Najafi, Farideh
Hollingsworth, Neusha
Buller, Leonard T.
Krueger, Chad A.
Patients With Previous COVID-19 Infection Can Safely Undergo Primary Total Joint Arthroplasty
title Patients With Previous COVID-19 Infection Can Safely Undergo Primary Total Joint Arthroplasty
title_full Patients With Previous COVID-19 Infection Can Safely Undergo Primary Total Joint Arthroplasty
title_fullStr Patients With Previous COVID-19 Infection Can Safely Undergo Primary Total Joint Arthroplasty
title_full_unstemmed Patients With Previous COVID-19 Infection Can Safely Undergo Primary Total Joint Arthroplasty
title_short Patients With Previous COVID-19 Infection Can Safely Undergo Primary Total Joint Arthroplasty
title_sort patients with previous covid-19 infection can safely undergo primary total joint arthroplasty
topic Primary Hip and Knee Arthroplasty
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622022/
https://www.ncbi.nlm.nih.gov/pubmed/36328105
http://dx.doi.org/10.1016/j.arth.2022.10.041
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