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Direct Ryanodine Receptor-2 Knockout in Primary Afferent Fibers Modestly Affects Neurological Recovery after Contusive Spinal Cord Injury

Neuronal ryanodine receptors (RyR) release calcium from internal stores and play a key role in synaptic plasticity, learning, and memory. Dysregulation of RyR function contributes to neurodegeneration and negatively impacts neurological recovery after spinal cord injury (SCI). However, the individua...

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Detalles Bibliográficos
Autores principales: Orem, Ben C., Morehouse, Johnny R., Ames, Spencer, Burke, Darlene A., Magnuson, David S.K., Stirling, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622210/
https://www.ncbi.nlm.nih.gov/pubmed/36337076
http://dx.doi.org/10.1089/neur.2022.0044