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Cell clusters softening triggers collective cell migration in vivo

Embryogenesis, tissue repair and cancer metastasis rely on collective cell migration. In vitro studies propose that cells are stiffer while migrating in stiff substrates, but softer when plated in compliant surfaces which are typically considered as non-permissive for migration. Here we show that ce...

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Detalles Bibliográficos
Autores principales: Marchant, Cristian L., Malmi-Kakkada, Abdul N., Espina, Jaime A., Barriga, Elias H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622418/
https://www.ncbi.nlm.nih.gov/pubmed/35970965
http://dx.doi.org/10.1038/s41563-022-01323-0