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CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tau

The aggregation of the microtubule-associated protein tau is a defining feature of Alzheimer’s disease and other tauopathies. Tau pathology is believed to be driven by free tau aggregates and tau carried within exosome-like extracellular vesicles, both of which propagate trans-synaptically and induc...

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Detalles Bibliográficos
Autores principales:	Polanco, Juan Carlos, Akimov, Yevhen, Fernandes, Avinash, Briner, Adam, Hand, Gabriel Rhys, van Roijen, Marloes, Balistreri, Giuseppe, Götz, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622425/ https://www.ncbi.nlm.nih.gov/pubmed/36316035 http://dx.doi.org/10.26508/lsa.202201689

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