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Cost-effectiveness of noninvasive telemedical interventional management in patients with heart failure: health economic analysis of the TIM-HF2 trial

BACKGROUND: Noninvasive remote patient management (RPM) in patients with heart failure (HF) has been shown to reduce the days lost due to unplanned cardiovascular hospital admissions and all-cause mortality in the Telemedical Interventional Management in Heart Failure II trial (TIM-HF2). The health...

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Autores principales: Sydow, Hanna, Prescher, Sandra, Koehler, Friedrich, Koehler, Kerstin, Dorenkamp, Marc, Spethmann, Sebastian, Westerhoff, Benjamin, Wagner, Christoph J., Liersch, Sebastian, Rebscher, Herbert, Wobbe-Ribinski, Stefanie, Rindfleisch, Heike, Müller-Riemenschneider, Falk, Willich, Stefan N., Reinhold, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622523/
https://www.ncbi.nlm.nih.gov/pubmed/34894273
http://dx.doi.org/10.1007/s00392-021-01980-2
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author Sydow, Hanna
Prescher, Sandra
Koehler, Friedrich
Koehler, Kerstin
Dorenkamp, Marc
Spethmann, Sebastian
Westerhoff, Benjamin
Wagner, Christoph J.
Liersch, Sebastian
Rebscher, Herbert
Wobbe-Ribinski, Stefanie
Rindfleisch, Heike
Müller-Riemenschneider, Falk
Willich, Stefan N.
Reinhold, Thomas
author_facet Sydow, Hanna
Prescher, Sandra
Koehler, Friedrich
Koehler, Kerstin
Dorenkamp, Marc
Spethmann, Sebastian
Westerhoff, Benjamin
Wagner, Christoph J.
Liersch, Sebastian
Rebscher, Herbert
Wobbe-Ribinski, Stefanie
Rindfleisch, Heike
Müller-Riemenschneider, Falk
Willich, Stefan N.
Reinhold, Thomas
author_sort Sydow, Hanna
collection PubMed
description BACKGROUND: Noninvasive remote patient management (RPM) in patients with heart failure (HF) has been shown to reduce the days lost due to unplanned cardiovascular hospital admissions and all-cause mortality in the Telemedical Interventional Management in Heart Failure II trial (TIM-HF2). The health economic implications of these findings are the focus of the present analyses from the payer perspective. METHODS AND RESULTS: A total of 1538 participants of the TIM-HF2 randomized controlled trial were assigned to the RPM and Usual Care group. Health claims data were available for 1450 patients (n = 715 RPM group, n = 735 Usual Care group), which represents 94.3% of the original TIM-HF2 patient population, were linked to primary data from the study documentation and evaluated in terms of the health care cost, total cost (accounting for intervention costs), costs per day alive and out of hospital (DAOH), and cost per quality-adjusted life year (QALY). The average health care costs per patient year amounted to € 14,412 (95% CI 13,284–15,539) in the RPM group and € 17,537 (95% CI 16,179–18,894) in the UC group. RPM led to cost savings of € 3125 per patient year (p = 0.001). After including the intervention costs, a cost saving of € 1758 per patient year remained (p = 0.048). CONCLUSION: The additional noninvasive telemedical interventional management in patients with HF was cost-effective compared to standard care alone, since such intervention was associated with overall cost savings and superior clinical effectiveness. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-96225232022-11-02 Cost-effectiveness of noninvasive telemedical interventional management in patients with heart failure: health economic analysis of the TIM-HF2 trial Sydow, Hanna Prescher, Sandra Koehler, Friedrich Koehler, Kerstin Dorenkamp, Marc Spethmann, Sebastian Westerhoff, Benjamin Wagner, Christoph J. Liersch, Sebastian Rebscher, Herbert Wobbe-Ribinski, Stefanie Rindfleisch, Heike Müller-Riemenschneider, Falk Willich, Stefan N. Reinhold, Thomas Clin Res Cardiol Original Paper BACKGROUND: Noninvasive remote patient management (RPM) in patients with heart failure (HF) has been shown to reduce the days lost due to unplanned cardiovascular hospital admissions and all-cause mortality in the Telemedical Interventional Management in Heart Failure II trial (TIM-HF2). The health economic implications of these findings are the focus of the present analyses from the payer perspective. METHODS AND RESULTS: A total of 1538 participants of the TIM-HF2 randomized controlled trial were assigned to the RPM and Usual Care group. Health claims data were available for 1450 patients (n = 715 RPM group, n = 735 Usual Care group), which represents 94.3% of the original TIM-HF2 patient population, were linked to primary data from the study documentation and evaluated in terms of the health care cost, total cost (accounting for intervention costs), costs per day alive and out of hospital (DAOH), and cost per quality-adjusted life year (QALY). The average health care costs per patient year amounted to € 14,412 (95% CI 13,284–15,539) in the RPM group and € 17,537 (95% CI 16,179–18,894) in the UC group. RPM led to cost savings of € 3125 per patient year (p = 0.001). After including the intervention costs, a cost saving of € 1758 per patient year remained (p = 0.048). CONCLUSION: The additional noninvasive telemedical interventional management in patients with HF was cost-effective compared to standard care alone, since such intervention was associated with overall cost savings and superior clinical effectiveness. GRAPHICAL ABSTRACT: [Image: see text] Springer Berlin Heidelberg 2021-12-11 2022 /pmc/articles/PMC9622523/ /pubmed/34894273 http://dx.doi.org/10.1007/s00392-021-01980-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Paper
Sydow, Hanna
Prescher, Sandra
Koehler, Friedrich
Koehler, Kerstin
Dorenkamp, Marc
Spethmann, Sebastian
Westerhoff, Benjamin
Wagner, Christoph J.
Liersch, Sebastian
Rebscher, Herbert
Wobbe-Ribinski, Stefanie
Rindfleisch, Heike
Müller-Riemenschneider, Falk
Willich, Stefan N.
Reinhold, Thomas
Cost-effectiveness of noninvasive telemedical interventional management in patients with heart failure: health economic analysis of the TIM-HF2 trial
title Cost-effectiveness of noninvasive telemedical interventional management in patients with heart failure: health economic analysis of the TIM-HF2 trial
title_full Cost-effectiveness of noninvasive telemedical interventional management in patients with heart failure: health economic analysis of the TIM-HF2 trial
title_fullStr Cost-effectiveness of noninvasive telemedical interventional management in patients with heart failure: health economic analysis of the TIM-HF2 trial
title_full_unstemmed Cost-effectiveness of noninvasive telemedical interventional management in patients with heart failure: health economic analysis of the TIM-HF2 trial
title_short Cost-effectiveness of noninvasive telemedical interventional management in patients with heart failure: health economic analysis of the TIM-HF2 trial
title_sort cost-effectiveness of noninvasive telemedical interventional management in patients with heart failure: health economic analysis of the tim-hf2 trial
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622523/
https://www.ncbi.nlm.nih.gov/pubmed/34894273
http://dx.doi.org/10.1007/s00392-021-01980-2
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