Cargando…

The prevalence of constipation in end-stage kidney disease patients: A cross-sectional observation study

The aim of our study was to determine the prevalence, distribution, and risk factors for constipation in peritoneal dialysis (PD) and hemodialysis (HD) patients in our center. In this cross-sectional study, 858 dialysis patients over 18 years of age (681 HD cases and 177 PD cases from our hospital)...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Liuping, Tang, Fang, Wang, Fengmei, Xie, Qinglei, Xia, Meixia, Jiang, Liangyunzi, Wang, Ze-Mu, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622587/
https://www.ncbi.nlm.nih.gov/pubmed/36316834
http://dx.doi.org/10.1097/MD.0000000000031552
_version_ 1784821805271220224
author Zhang, Liuping
Tang, Fang
Wang, Fengmei
Xie, Qinglei
Xia, Meixia
Jiang, Liangyunzi
Wang, Ze-Mu
Wang, Bin
author_facet Zhang, Liuping
Tang, Fang
Wang, Fengmei
Xie, Qinglei
Xia, Meixia
Jiang, Liangyunzi
Wang, Ze-Mu
Wang, Bin
author_sort Zhang, Liuping
collection PubMed
description The aim of our study was to determine the prevalence, distribution, and risk factors for constipation in peritoneal dialysis (PD) and hemodialysis (HD) patients in our center. In this cross-sectional study, 858 dialysis patients over 18 years of age (681 HD cases and 177 PD cases from our hospital) were enrolled. A constipation assessment scale (CAS) questionnaire was used to evaluate constipation status. Logistic regression analysis was performed to define independent risk factors for CAS scores. The prevalence of constipation in HD and PD patients was 52.7% and 77.4%, respectively. The mean CAS score in HD and PD patients was 1.73 ± 2.31 and 2.42 ± 2.34, respectively. Age ≥ 65 and diabetic kidney disease for renal failure were independent risk factors associated with constipation in the HD population (OR = 1.67, 95% CI: 1.15–2.90, P = .019; OR = 3.31, 95% CI: 1.65–6.11, P < .001, respectively). In the PD population, only serum prealbumin was independently associated with constipation (OR = 0.88, 95% CI: 0.79–0.96, P = .007). The multivariable logistic regression analysis demonstrated that PD modality, age ≥ 65 and diabetic kidney disease for renal failure were independent risk factors for constipation (OR = 2.15, 95% CI: 1.41–3.32, P < .001; OR = 1.65, 95% CI: 1.13–2.33, P = .003; OR = 3.19, 95% CI: 1.76–5.093, P < .001, respectively). The prevalence of constipation in PD patients was higher than that in HD patients in our center. PD modality for renal replacement therapy, age ≥ 65 and diabetic kidney disease for renal failure were closely associated with constipation in dialysis patients.
format Online
Article
Text
id pubmed-9622587
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-96225872022-11-03 The prevalence of constipation in end-stage kidney disease patients: A cross-sectional observation study Zhang, Liuping Tang, Fang Wang, Fengmei Xie, Qinglei Xia, Meixia Jiang, Liangyunzi Wang, Ze-Mu Wang, Bin Medicine (Baltimore) 5200 The aim of our study was to determine the prevalence, distribution, and risk factors for constipation in peritoneal dialysis (PD) and hemodialysis (HD) patients in our center. In this cross-sectional study, 858 dialysis patients over 18 years of age (681 HD cases and 177 PD cases from our hospital) were enrolled. A constipation assessment scale (CAS) questionnaire was used to evaluate constipation status. Logistic regression analysis was performed to define independent risk factors for CAS scores. The prevalence of constipation in HD and PD patients was 52.7% and 77.4%, respectively. The mean CAS score in HD and PD patients was 1.73 ± 2.31 and 2.42 ± 2.34, respectively. Age ≥ 65 and diabetic kidney disease for renal failure were independent risk factors associated with constipation in the HD population (OR = 1.67, 95% CI: 1.15–2.90, P = .019; OR = 3.31, 95% CI: 1.65–6.11, P < .001, respectively). In the PD population, only serum prealbumin was independently associated with constipation (OR = 0.88, 95% CI: 0.79–0.96, P = .007). The multivariable logistic regression analysis demonstrated that PD modality, age ≥ 65 and diabetic kidney disease for renal failure were independent risk factors for constipation (OR = 2.15, 95% CI: 1.41–3.32, P < .001; OR = 1.65, 95% CI: 1.13–2.33, P = .003; OR = 3.19, 95% CI: 1.76–5.093, P < .001, respectively). The prevalence of constipation in PD patients was higher than that in HD patients in our center. PD modality for renal replacement therapy, age ≥ 65 and diabetic kidney disease for renal failure were closely associated with constipation in dialysis patients. Lippincott Williams & Wilkins 2022-10-28 /pmc/articles/PMC9622587/ /pubmed/36316834 http://dx.doi.org/10.1097/MD.0000000000031552 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 5200
Zhang, Liuping
Tang, Fang
Wang, Fengmei
Xie, Qinglei
Xia, Meixia
Jiang, Liangyunzi
Wang, Ze-Mu
Wang, Bin
The prevalence of constipation in end-stage kidney disease patients: A cross-sectional observation study
title The prevalence of constipation in end-stage kidney disease patients: A cross-sectional observation study
title_full The prevalence of constipation in end-stage kidney disease patients: A cross-sectional observation study
title_fullStr The prevalence of constipation in end-stage kidney disease patients: A cross-sectional observation study
title_full_unstemmed The prevalence of constipation in end-stage kidney disease patients: A cross-sectional observation study
title_short The prevalence of constipation in end-stage kidney disease patients: A cross-sectional observation study
title_sort prevalence of constipation in end-stage kidney disease patients: a cross-sectional observation study
topic 5200
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622587/
https://www.ncbi.nlm.nih.gov/pubmed/36316834
http://dx.doi.org/10.1097/MD.0000000000031552
work_keys_str_mv AT zhangliuping theprevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT tangfang theprevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT wangfengmei theprevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT xieqinglei theprevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT xiameixia theprevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT jiangliangyunzi theprevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT wangzemu theprevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT wangbin theprevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT zhangliuping prevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT tangfang prevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT wangfengmei prevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT xieqinglei prevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT xiameixia prevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT jiangliangyunzi prevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT wangzemu prevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy
AT wangbin prevalenceofconstipationinendstagekidneydiseasepatientsacrosssectionalobservationstudy