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Rate and risk factors of metabolic components and component combinations according to hypertension status in Tibetans in a cross-sectional study

To estimate the prevalence of metabolic syndrome (MS) and metabolic components and their associated factors and component combinations according to hypertension status in Tibetans living at high altitude. Multistage sampling of 1473 participants (799 hypertensive patients and 674 normotensive subjec...

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Autores principales: Hu, Jihong, Thompson, Brian, Wang, Shuxia, Guo, Minhao, Yan, Chunjuan, Ding, Fengfeng, Guo, Peng, Chen, Li, Cao, Zhuoma, Wang, Jianzong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622625/
https://www.ncbi.nlm.nih.gov/pubmed/36316919
http://dx.doi.org/10.1097/MD.0000000000031320
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author Hu, Jihong
Thompson, Brian
Wang, Shuxia
Guo, Minhao
Yan, Chunjuan
Ding, Fengfeng
Guo, Peng
Chen, Li
Cao, Zhuoma
Wang, Jianzong
author_facet Hu, Jihong
Thompson, Brian
Wang, Shuxia
Guo, Minhao
Yan, Chunjuan
Ding, Fengfeng
Guo, Peng
Chen, Li
Cao, Zhuoma
Wang, Jianzong
author_sort Hu, Jihong
collection PubMed
description To estimate the prevalence of metabolic syndrome (MS) and metabolic components and their associated factors and component combinations according to hypertension status in Tibetans living at high altitude. Multistage sampling of 1473 participants (799 hypertensive patients and 674 normotensive subjects). MS prevalence and the number of metabolic components ≥ 3 were significantly higher in the hypertensive than normotensives. In hypertensive patients, the most common component was central obesity and it combined with: high blood pressure, in those with 2 risk factors, plus fasting hyperglycemia, in those with 3 risk factors, and high triglyceride, in those with 4 risk factors. In normotensive subjects, the most common single component was low high-density-lipoprotein cholesterol, and most component combination included central obesity and hyperglycemia in those with 2 risk factors, plus high blood pressure in those with 3 risk factors, and high triglycerides in those with 4 risk factors. Body mass index and female both were associated with increased possibilities of MS in hypertensive and normotensive participants. Low incoming, and high educational levels were associated with an elevated probability of MS in normotensive Tibetans also. The priority of prevention from cardiovascular diseases by targeting metabolic components in the hypertensive was different from normotensives. Different MS components had various lifestyle and socioeconomic factors.
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spelling pubmed-96226252022-11-03 Rate and risk factors of metabolic components and component combinations according to hypertension status in Tibetans in a cross-sectional study Hu, Jihong Thompson, Brian Wang, Shuxia Guo, Minhao Yan, Chunjuan Ding, Fengfeng Guo, Peng Chen, Li Cao, Zhuoma Wang, Jianzong Medicine (Baltimore) 4400 To estimate the prevalence of metabolic syndrome (MS) and metabolic components and their associated factors and component combinations according to hypertension status in Tibetans living at high altitude. Multistage sampling of 1473 participants (799 hypertensive patients and 674 normotensive subjects). MS prevalence and the number of metabolic components ≥ 3 were significantly higher in the hypertensive than normotensives. In hypertensive patients, the most common component was central obesity and it combined with: high blood pressure, in those with 2 risk factors, plus fasting hyperglycemia, in those with 3 risk factors, and high triglyceride, in those with 4 risk factors. In normotensive subjects, the most common single component was low high-density-lipoprotein cholesterol, and most component combination included central obesity and hyperglycemia in those with 2 risk factors, plus high blood pressure in those with 3 risk factors, and high triglycerides in those with 4 risk factors. Body mass index and female both were associated with increased possibilities of MS in hypertensive and normotensive participants. Low incoming, and high educational levels were associated with an elevated probability of MS in normotensive Tibetans also. The priority of prevention from cardiovascular diseases by targeting metabolic components in the hypertensive was different from normotensives. Different MS components had various lifestyle and socioeconomic factors. Lippincott Williams & Wilkins 2022-10-28 /pmc/articles/PMC9622625/ /pubmed/36316919 http://dx.doi.org/10.1097/MD.0000000000031320 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 4400
Hu, Jihong
Thompson, Brian
Wang, Shuxia
Guo, Minhao
Yan, Chunjuan
Ding, Fengfeng
Guo, Peng
Chen, Li
Cao, Zhuoma
Wang, Jianzong
Rate and risk factors of metabolic components and component combinations according to hypertension status in Tibetans in a cross-sectional study
title Rate and risk factors of metabolic components and component combinations according to hypertension status in Tibetans in a cross-sectional study
title_full Rate and risk factors of metabolic components and component combinations according to hypertension status in Tibetans in a cross-sectional study
title_fullStr Rate and risk factors of metabolic components and component combinations according to hypertension status in Tibetans in a cross-sectional study
title_full_unstemmed Rate and risk factors of metabolic components and component combinations according to hypertension status in Tibetans in a cross-sectional study
title_short Rate and risk factors of metabolic components and component combinations according to hypertension status in Tibetans in a cross-sectional study
title_sort rate and risk factors of metabolic components and component combinations according to hypertension status in tibetans in a cross-sectional study
topic 4400
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622625/
https://www.ncbi.nlm.nih.gov/pubmed/36316919
http://dx.doi.org/10.1097/MD.0000000000031320
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