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Characterization of an Escherichia coli-derived triple-type chimeric vaccine against human papillomavirus types 39, 68 and 70

In vaccinology, a potent immunogen has two prerequisite attributes—antigenicity and immunogenicity. We have rational designed a triple-type HPV vaccine against HPV58, −33 and −52 covered in Gardasil 9 based on the sequence homology and similar surface loop structure of L1 protein, which is related t...

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Autores principales:	Qian, Ciying, Yang, Yurou, Xu, Qin, Wang, Zhiping, Chen, Jie, Chi, Xin, Yu, Miao, Gao, Fei, Xu, Yujie, Lu, Yihan, Sun, Hui, Shen, Jingjia, Wang, Daning, Zhou, Lizhi, Li, Tingting, Wang, Yingbin, Zheng, Qingbing, Yu, Hai, Zhang, Jun, Gu, Ying, Xia, Ningshao, Li, Shaowei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622684/ https://www.ncbi.nlm.nih.gov/pubmed/36316367 http://dx.doi.org/10.1038/s41541-022-00557-y

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