CUR5g, a novel autophagy inhibitor, exhibits potent synergistic anticancer effects with cisplatin against non-small-cell lung cancer

Autophagy, a highly conserved degradation process of eukaryotic cells, has been proven to be closely related to chemoresistance and metastasis of non-small-cell lung cancer (NSCLC). Autophagy inhibitors, such as chloroquine (CQ) and its derivative hydroxychloroquine (HCQ), has been shown to mediate...

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Detalles Bibliográficos
Autores principales: Chen, Jingxuan, Shen, Yunpeng, Wu, Bowen, Yang, Peichang, Sun, Gangchun, Liu, Xiaoting, Qiang, Pengfei, Gao, Yamei, Sha, Fangfang, Li, Zirui, Zhang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622744/
https://www.ncbi.nlm.nih.gov/pubmed/36316321
http://dx.doi.org/10.1038/s41420-022-01217-9

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