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Choice of injection time of conscious sedation and its impact on pain control in colonoscopy

PURPOSE: The aim of this study was to identify the effect of different injection times on pain during colonoscopy procedure. METHODS: In this retrospective study, the data of patients who underwent colonoscopy from June 2020 to September 2020 were assessed to investigate the effect of different inje...

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Autores principales: Su, Mingli, Chen, Tingting, Zhong, Qinghua, Lin, Dezheng, Liu, Wei, Su, Yuping, Deng, Jiaxin, Zhang, Jiawei, Hu, Jiancong, Guo, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622756/
https://www.ncbi.nlm.nih.gov/pubmed/36329974
http://dx.doi.org/10.3389/fsurg.2022.886129
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author Su, Mingli
Chen, Tingting
Zhong, Qinghua
Lin, Dezheng
Liu, Wei
Su, Yuping
Deng, Jiaxin
Zhang, Jiawei
Hu, Jiancong
Guo, Xuefeng
author_facet Su, Mingli
Chen, Tingting
Zhong, Qinghua
Lin, Dezheng
Liu, Wei
Su, Yuping
Deng, Jiaxin
Zhang, Jiawei
Hu, Jiancong
Guo, Xuefeng
author_sort Su, Mingli
collection PubMed
description PURPOSE: The aim of this study was to identify the effect of different injection times on pain during colonoscopy procedure. METHODS: In this retrospective study, the data of patients who underwent colonoscopy from June 2020 to September 2020 were assessed to investigate the effect of different injection time of sedative drugs (midazolam and dezocine). The primary endpoint was evaluating the pain intensity of the patients using visual analogue scale (VAS) immediately after colonoscopy . RESULTS: A total of 152 patients were eligible for this study. Of them, 76 received midazolam and dezocine injection 1 min prior to the colonoscopy procedure (the 1 Min group) and the other 76 patients received the injection 3 min prior to the procedure (the 3 Min group). The vital signs of all patients were stable except for one patient who was diagnosed with inflammatory bowel disease in the 3 Min group. A transient drop in blood pressure for this patient was observed during colonoscopy but returned to normal after general treatment. The two groups had similar rates of cecal intubation (84.21% vs. 90.97%, P = 0.22), addition of sedative drugs during procedure (2.63% vs. 5.26%, P = 0.68), and adequate bowel preparation (Boston Bowel Preparation Scale ≥6, 61.84% vs. 61.84%, P = 1.0). However, patients in the 3 Min group had significantly lower VAS than those in the 1 Min group [0 (0, 1) vs. 1 (0, 2), P = 0.041]. CONCLUSION: The timing of drug injection during conscious sedation may affect pain control during colonoscopy, with 3 min prior to the procedure showing lower VAS.
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spelling pubmed-96227562022-11-02 Choice of injection time of conscious sedation and its impact on pain control in colonoscopy Su, Mingli Chen, Tingting Zhong, Qinghua Lin, Dezheng Liu, Wei Su, Yuping Deng, Jiaxin Zhang, Jiawei Hu, Jiancong Guo, Xuefeng Front Surg Surgery PURPOSE: The aim of this study was to identify the effect of different injection times on pain during colonoscopy procedure. METHODS: In this retrospective study, the data of patients who underwent colonoscopy from June 2020 to September 2020 were assessed to investigate the effect of different injection time of sedative drugs (midazolam and dezocine). The primary endpoint was evaluating the pain intensity of the patients using visual analogue scale (VAS) immediately after colonoscopy . RESULTS: A total of 152 patients were eligible for this study. Of them, 76 received midazolam and dezocine injection 1 min prior to the colonoscopy procedure (the 1 Min group) and the other 76 patients received the injection 3 min prior to the procedure (the 3 Min group). The vital signs of all patients were stable except for one patient who was diagnosed with inflammatory bowel disease in the 3 Min group. A transient drop in blood pressure for this patient was observed during colonoscopy but returned to normal after general treatment. The two groups had similar rates of cecal intubation (84.21% vs. 90.97%, P = 0.22), addition of sedative drugs during procedure (2.63% vs. 5.26%, P = 0.68), and adequate bowel preparation (Boston Bowel Preparation Scale ≥6, 61.84% vs. 61.84%, P = 1.0). However, patients in the 3 Min group had significantly lower VAS than those in the 1 Min group [0 (0, 1) vs. 1 (0, 2), P = 0.041]. CONCLUSION: The timing of drug injection during conscious sedation may affect pain control during colonoscopy, with 3 min prior to the procedure showing lower VAS. Frontiers Media S.A. 2022-10-18 /pmc/articles/PMC9622756/ /pubmed/36329974 http://dx.doi.org/10.3389/fsurg.2022.886129 Text en © 2022 Su, Chen, Zhong, Lin, Liu, Su, Deng, Zhang, Hu and Guo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Su, Mingli
Chen, Tingting
Zhong, Qinghua
Lin, Dezheng
Liu, Wei
Su, Yuping
Deng, Jiaxin
Zhang, Jiawei
Hu, Jiancong
Guo, Xuefeng
Choice of injection time of conscious sedation and its impact on pain control in colonoscopy
title Choice of injection time of conscious sedation and its impact on pain control in colonoscopy
title_full Choice of injection time of conscious sedation and its impact on pain control in colonoscopy
title_fullStr Choice of injection time of conscious sedation and its impact on pain control in colonoscopy
title_full_unstemmed Choice of injection time of conscious sedation and its impact on pain control in colonoscopy
title_short Choice of injection time of conscious sedation and its impact on pain control in colonoscopy
title_sort choice of injection time of conscious sedation and its impact on pain control in colonoscopy
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622756/
https://www.ncbi.nlm.nih.gov/pubmed/36329974
http://dx.doi.org/10.3389/fsurg.2022.886129
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