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National and subnational short-term forecasting of COVID-19 in Germany and Poland during early 2021

BACKGROUND: During the COVID-19 pandemic there has been a strong interest in forecasts of the short-term development of epidemiological indicators to inform decision makers. In this study we evaluate probabilistic real-time predictions of confirmed cases and deaths from COVID-19 in Germany and Polan...

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Autores principales: Bracher, Johannes, Wolffram, Daniel, Deuschel, Jannik, Görgen, Konstantin, Ketterer, Jakob L., Ullrich, Alexander, Abbott, Sam, Barbarossa, Maria V., Bertsimas, Dimitris, Bhatia, Sangeeta, Bodych, Marcin, Bosse, Nikos I., Burgard, Jan Pablo, Castro, Lauren, Fairchild, Geoffrey, Fiedler, Jochen, Fuhrmann, Jan, Funk, Sebastian, Gambin, Anna, Gogolewski, Krzysztof, Heyder, Stefan, Hotz, Thomas, Kheifetz, Yuri, Kirsten, Holger, Krueger, Tyll, Krymova, Ekaterina, Leithäuser, Neele, Li, Michael L., Meinke, Jan H., Miasojedow, Błażej, Michaud, Isaac J., Mohring, Jan, Nouvellet, Pierre, Nowosielski, Jedrzej M., Ozanski, Tomasz, Radwan, Maciej, Rakowski, Franciszek, Scholz, Markus, Soni, Saksham, Srivastava, Ajitesh, Gneiting, Tilmann, Schienle, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622804/
https://www.ncbi.nlm.nih.gov/pubmed/36352249
http://dx.doi.org/10.1038/s43856-022-00191-8
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author Bracher, Johannes
Wolffram, Daniel
Deuschel, Jannik
Görgen, Konstantin
Ketterer, Jakob L.
Ullrich, Alexander
Abbott, Sam
Barbarossa, Maria V.
Bertsimas, Dimitris
Bhatia, Sangeeta
Bodych, Marcin
Bosse, Nikos I.
Burgard, Jan Pablo
Castro, Lauren
Fairchild, Geoffrey
Fiedler, Jochen
Fuhrmann, Jan
Funk, Sebastian
Gambin, Anna
Gogolewski, Krzysztof
Heyder, Stefan
Hotz, Thomas
Kheifetz, Yuri
Kirsten, Holger
Krueger, Tyll
Krymova, Ekaterina
Leithäuser, Neele
Li, Michael L.
Meinke, Jan H.
Miasojedow, Błażej
Michaud, Isaac J.
Mohring, Jan
Nouvellet, Pierre
Nowosielski, Jedrzej M.
Ozanski, Tomasz
Radwan, Maciej
Rakowski, Franciszek
Scholz, Markus
Soni, Saksham
Srivastava, Ajitesh
Gneiting, Tilmann
Schienle, Melanie
author_facet Bracher, Johannes
Wolffram, Daniel
Deuschel, Jannik
Görgen, Konstantin
Ketterer, Jakob L.
Ullrich, Alexander
Abbott, Sam
Barbarossa, Maria V.
Bertsimas, Dimitris
Bhatia, Sangeeta
Bodych, Marcin
Bosse, Nikos I.
Burgard, Jan Pablo
Castro, Lauren
Fairchild, Geoffrey
Fiedler, Jochen
Fuhrmann, Jan
Funk, Sebastian
Gambin, Anna
Gogolewski, Krzysztof
Heyder, Stefan
Hotz, Thomas
Kheifetz, Yuri
Kirsten, Holger
Krueger, Tyll
Krymova, Ekaterina
Leithäuser, Neele
Li, Michael L.
Meinke, Jan H.
Miasojedow, Błażej
Michaud, Isaac J.
Mohring, Jan
Nouvellet, Pierre
Nowosielski, Jedrzej M.
Ozanski, Tomasz
Radwan, Maciej
Rakowski, Franciszek
Scholz, Markus
Soni, Saksham
Srivastava, Ajitesh
Gneiting, Tilmann
Schienle, Melanie
author_sort Bracher, Johannes
collection PubMed
description BACKGROUND: During the COVID-19 pandemic there has been a strong interest in forecasts of the short-term development of epidemiological indicators to inform decision makers. In this study we evaluate probabilistic real-time predictions of confirmed cases and deaths from COVID-19 in Germany and Poland for the period from January through April 2021. METHODS: We evaluate probabilistic real-time predictions of confirmed cases and deaths from COVID-19 in Germany and Poland. These were issued by 15 different forecasting models, run by independent research teams. Moreover, we study the performance of combined ensemble forecasts. Evaluation of probabilistic forecasts is based on proper scoring rules, along with interval coverage proportions to assess calibration. The presented work is part of a pre-registered evaluation study. RESULTS: We find that many, though not all, models outperform a simple baseline model up to four weeks ahead for the considered targets. Ensemble methods show very good relative performance. The addressed time period is characterized by rather stable non-pharmaceutical interventions in both countries, making short-term predictions more straightforward than in previous periods. However, major trend changes in reported cases, like the rebound in cases due to the rise of the B.1.1.7 (Alpha) variant in March 2021, prove challenging to predict. CONCLUSIONS: Multi-model approaches can help to improve the performance of epidemiological forecasts. However, while death numbers can be predicted with some success based on current case and hospitalization data, predictability of case numbers remains low beyond quite short time horizons. Additional data sources including sequencing and mobility data, which were not extensively used in the present study, may help to improve performance.
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spelling pubmed-96228042022-11-02 National and subnational short-term forecasting of COVID-19 in Germany and Poland during early 2021 Bracher, Johannes Wolffram, Daniel Deuschel, Jannik Görgen, Konstantin Ketterer, Jakob L. Ullrich, Alexander Abbott, Sam Barbarossa, Maria V. Bertsimas, Dimitris Bhatia, Sangeeta Bodych, Marcin Bosse, Nikos I. Burgard, Jan Pablo Castro, Lauren Fairchild, Geoffrey Fiedler, Jochen Fuhrmann, Jan Funk, Sebastian Gambin, Anna Gogolewski, Krzysztof Heyder, Stefan Hotz, Thomas Kheifetz, Yuri Kirsten, Holger Krueger, Tyll Krymova, Ekaterina Leithäuser, Neele Li, Michael L. Meinke, Jan H. Miasojedow, Błażej Michaud, Isaac J. Mohring, Jan Nouvellet, Pierre Nowosielski, Jedrzej M. Ozanski, Tomasz Radwan, Maciej Rakowski, Franciszek Scholz, Markus Soni, Saksham Srivastava, Ajitesh Gneiting, Tilmann Schienle, Melanie Commun Med (Lond) Article BACKGROUND: During the COVID-19 pandemic there has been a strong interest in forecasts of the short-term development of epidemiological indicators to inform decision makers. In this study we evaluate probabilistic real-time predictions of confirmed cases and deaths from COVID-19 in Germany and Poland for the period from January through April 2021. METHODS: We evaluate probabilistic real-time predictions of confirmed cases and deaths from COVID-19 in Germany and Poland. These were issued by 15 different forecasting models, run by independent research teams. Moreover, we study the performance of combined ensemble forecasts. Evaluation of probabilistic forecasts is based on proper scoring rules, along with interval coverage proportions to assess calibration. The presented work is part of a pre-registered evaluation study. RESULTS: We find that many, though not all, models outperform a simple baseline model up to four weeks ahead for the considered targets. Ensemble methods show very good relative performance. The addressed time period is characterized by rather stable non-pharmaceutical interventions in both countries, making short-term predictions more straightforward than in previous periods. However, major trend changes in reported cases, like the rebound in cases due to the rise of the B.1.1.7 (Alpha) variant in March 2021, prove challenging to predict. CONCLUSIONS: Multi-model approaches can help to improve the performance of epidemiological forecasts. However, while death numbers can be predicted with some success based on current case and hospitalization data, predictability of case numbers remains low beyond quite short time horizons. Additional data sources including sequencing and mobility data, which were not extensively used in the present study, may help to improve performance. Nature Publishing Group UK 2022-10-31 /pmc/articles/PMC9622804/ /pubmed/36352249 http://dx.doi.org/10.1038/s43856-022-00191-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Bracher, Johannes
Wolffram, Daniel
Deuschel, Jannik
Görgen, Konstantin
Ketterer, Jakob L.
Ullrich, Alexander
Abbott, Sam
Barbarossa, Maria V.
Bertsimas, Dimitris
Bhatia, Sangeeta
Bodych, Marcin
Bosse, Nikos I.
Burgard, Jan Pablo
Castro, Lauren
Fairchild, Geoffrey
Fiedler, Jochen
Fuhrmann, Jan
Funk, Sebastian
Gambin, Anna
Gogolewski, Krzysztof
Heyder, Stefan
Hotz, Thomas
Kheifetz, Yuri
Kirsten, Holger
Krueger, Tyll
Krymova, Ekaterina
Leithäuser, Neele
Li, Michael L.
Meinke, Jan H.
Miasojedow, Błażej
Michaud, Isaac J.
Mohring, Jan
Nouvellet, Pierre
Nowosielski, Jedrzej M.
Ozanski, Tomasz
Radwan, Maciej
Rakowski, Franciszek
Scholz, Markus
Soni, Saksham
Srivastava, Ajitesh
Gneiting, Tilmann
Schienle, Melanie
National and subnational short-term forecasting of COVID-19 in Germany and Poland during early 2021
title National and subnational short-term forecasting of COVID-19 in Germany and Poland during early 2021
title_full National and subnational short-term forecasting of COVID-19 in Germany and Poland during early 2021
title_fullStr National and subnational short-term forecasting of COVID-19 in Germany and Poland during early 2021
title_full_unstemmed National and subnational short-term forecasting of COVID-19 in Germany and Poland during early 2021
title_short National and subnational short-term forecasting of COVID-19 in Germany and Poland during early 2021
title_sort national and subnational short-term forecasting of covid-19 in germany and poland during early 2021
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622804/
https://www.ncbi.nlm.nih.gov/pubmed/36352249
http://dx.doi.org/10.1038/s43856-022-00191-8
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