NOP53 undergoes liquid-liquid phase separation and promotes tumor radio-resistance

Aberrant DNA damage response (DDR) axis remains the major molecular mechanism for tumor radio-resistance. We recently characterized liquid-liquid phase separation (LLPS) as an essential mechanism of DDR, and identified several key DDR factors as potential LLPS proteins, including nucleolar protein N...

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Detalles Bibliográficos
Autores principales: Shi, Jie, Chen, Si-Ying, Shen, Xiao-Ting, Yin, Xin-Ke, Zhao, Wan-Wen, Bai, Shao-Mei, Feng, Wei-Xing, Feng, Li-Li, Qin, Caolitao, Zheng, Jian, Wang, Yun-Long, Fan, Xin-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622906/
https://www.ncbi.nlm.nih.gov/pubmed/36316314
http://dx.doi.org/10.1038/s41420-022-01226-8

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